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Hepcidin 25 anticorps (AA 60-84) (HRP)

HEPC25 Reactivité: Souris, Rat IHC (p) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712656
  • Antigène Voir toutes Hepcidin 25 (HEPC25) Anticorps
    Hepcidin 25 (HEPC25)
    Épitope
    • 29
    • 1
    • 1
    AA 60-84
    Reactivité
    • 16
    • 15
    • 14
    Souris, Rat
    Hôte
    • 31
    Lapin
    Clonalité
    • 31
    Polyclonal
    Conjugué
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Hepcidin 25 est conjugé à/à la HRP
    Application
    • 26
    • 17
    • 13
    • 5
    • 5
    • 3
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from rat Hepcidin
    Isotype
    IgG
    Top Product
    Discover our top product HEPC25 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Hepcidin 25 (HEPC25)
    Autre désignation
    Hepcidin 25 (HEPC25 Produits)
    Synonymes
    anticorps HEPC, anticorps HFE2B, anticorps LEAP1, anticorps PLTR, anticorps hepcidin antimicrobial peptide, anticorps HAMP
    Sujet

    Synonyms: Hamp, HEPC, HEPC_RAT, HEPC_MOUSE, Hepc20, Hepc25, HEPCIDIN, Hepcidin, Hepcidin 20, Hepcidin 25, Hepcidin antimicrobial peptide, Hepcidin-20, Hepcidin25, HFE2, HFE2B, LEAP 1, LEAP-1, LEAP1, Liver expressed antimicrobial peptide, Liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor.

    Background: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].

    ID gène
    84604
    UniProt
    Q99MH3
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