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TYROBP anticorps (TYRO Protein tyrosine Kinase Binding Protein) (PE)

Détail du produit anti-TYROBP anticorps No. ABIN1712671, Fournisseur: Connectez-vous pour afficher
Antigène
  • TYROBP
  • DAP12
  • tyrpbp
  • Karap
  • KARAP
  • PLOSL
  • Ly83
  • dap12
  • TYRO protein tyrosine kinase binding protein
  • Tyro protein tyrosine kinase binding protein
  • TYROBP
  • tyrobp
  • Tyrobp
Reactivité
Humain
91
25
22
2
2
2
2
1
Hôte
Lapin
75
16
6
Clonalité
Polyclonal
Conjugué
Cet anticorp TYROBP est conjugé à/à la PE
4
4
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS)
62
46
26
23
20
19
2
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human DAP12
Isotype IgG
Purification Purified by Protein A.
Autre désignation Dap12 (TYROBP Antibody Extrait)
Sujet

This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]

Subcellular location: Extracellular


Synonyms: DAP 12, DAP12, DNAX activation protein 12, DNAX-activation protein 12, KAR-associated protein, KARAP, Killer activating receptor associated protein, Killer-activating receptor-associated protein, PLOSL, TYOBP_HUMAN, TYRO protein tyrosine kinase binding protein, TYRO protein tyrosine kinase-binding protein, TYROBP.
Domaine de recherche Signaling
Indications d'application FCM(1:20-100)
Commentaires

Exitation/Emission: 480,565nm/578nm

Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months