G Protein-Coupled Receptor 77 (GPR77) anticorps (PE)

Détails pour le produit réf. ABIN1712676, Fournisseur: Connectez-vous pour afficher
Antigène
  • GPR77
  • C5L2
  • GPF77
  • E030029A11Rik
  • Gpr77
  • G protein-coupled receptor 77
  • complement component 5a receptor 2
  • GPR77
  • C5AR2
  • C5ar2
Reactivité
Humain
98
5
4
2
2
1
Hôte
Lapin
87
11
1
Clonalité
Polyclonal
Conjugué
PE
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS)
41
31
26
25
10
7
2
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human GPF77
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gpr77 (GPR77 Antibody Extrait)
Sujet

Anaphylatoxin, a chemotactic and inflammatory peptide, is a receptor for C5a anaphylatoxin chemotactic receptor (C5L2), also designated G protein-coupled receptor 77. C5L2 is an integral membrane protein that belongs to the Gprotein-coupled receptor 1 family. C5L2 weakly couples to Gi-mediated signaling pathways and is widely expressed in the hippocampus, hypothalamus, pons, frontal cortex and liver. It is coexpressed with the C5a receptor (C5AR) on polymorphonuclear neutrophils and may modulate the activity of C5AR. The function of the C5a receptors, particularly that of C5L2, is still unclear. Research suggests that C5L2 may be required for the in vitro release of high mobility group box 1 protein (HMGB1).

Subcellular location: Extracellular


Synonyms: C5a anaphylatoxin chemotactic receptor C5L2, C5ARL_HUMAN, C5L2, E030029A11Rik, G protein coupled receptor 77, G protein coupled receptor C5L2, G-protein coupled receptor 77, GPF77, GPR77, GPCR GPR77.
ID gène 27202
Domaine de recherche Signaling
Indications d'application FCM(1:20-100)
Commentaires

Exitation/Emission: 480,565nm/578nm

Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months