TCR alpha anticorps (PE)

Détails pour le produit réf. ABIN1712687, Fournisseur: Connectez-vous pour afficher
Antigène
  • TCR-alpha
  • si:dz172d23.42
  • Tcralpha
  • TCRA
  • si:busm1-172d23.42
  • T cell receptor alpha chain
  • T cell receptor alpha constant
  • si:busm1-172d23.42
  • Tcra
  • TRAC
Reactivité
Humain, Souris
71
16
2
1
Hôte
Lapin
40
31
Clonalité
Polyclonal
Conjugué
PE
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
42
38
36
15
13
9
8
4
3
Options
Fournisseur
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Immunogène KLH conjugated synthetic peptide derived from human TCR alpha
Isotype IgG
Purification Purified by Protein A.
Sujet

Maturation of cytotoxic T lymphocytes is mediated in part by a structure on the T cell surface known as the T cell antigen receptor (TCR) complex. The pre-TCR complex consists of pre-TCR i±, pre-TCR i²and CD3, which together help coordinate early thymocyte development. Pre-TCR i± chain is a type I transmembrane glycoprotein with an extracellular region similar to the constant domain of the immunoglobulin supergene family. Notch3 transgenic mice lacking pre-TCR i± inhibits tumor development. In humans, acute lymphoblastic leukemias (ALL) in remission have lower transcript levels of Notch3, HES-1 and pre-TCR i± transcripts a and b relative to proliferating ALLs. The human pre-TCR i± gene is expressed in immature T cells and maps to chromosome 6p21.3.

Subcellular location: Extracellular


Synonyms: T cell antigen receptor alpha polypeptide,T cell receptor alpha,T cell receptor alpha locus,TCRA,TCRD,TRA,PTCRA_HUMAN.
ID gène 171558
Domaine de recherche Stem Cells, Hematopoietic Progenitors, Adaptive Immunity
Indications d'application FCM(1:20-100)
Commentaires

Exitation/Emission: 480,565nm/578nm

Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months