FXYD6 anticorps (FXYD Domain Containing Ion Transport Regulator 6) (PE)

Details for Product anti-FXYD6 Antibody No. ABIN1712694, Fournisseur: Connectez-vous pour afficher
Antigène
  • 0610030I18Rik
  • Php
  • FXYD domain containing ion transport regulator 6
  • FXYD domain-containing ion transport regulator 6
  • FXYD6
  • Fxyd6
Reactivité
Humain, Souris, Rat (Rattus)
30
22
22
Hôte
Lapin
30
Clonalité
Polyclonal
Conjugué
Cet anticorp FXYD6 est conjugé à/à la PE
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
16
13
9
7
5
4
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human FXYD6
Isotype IgG
Purification Purified by Protein A.
Autre désignation Fxyd6 (FXYD6 Antibody Extrait)
Sujet

The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing seven invariant and six conserved amino acids. Members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD2 (the g subunit of the Na+/K+-ATPase), FXYD3 (Mat8, mammary tumor protein), FXYD4 (CHIF) and FXYD5 (RIC). FXYD6 is expressed in various epithelial cells bordering the endolymph space and in the auditory neurons. FXYD6 co-localizes with Na+/K+-ATPase in the stria vascularis and can be co-immunoprecipitated with Na+/K+-ATPase. After expression, FXYD6 associates with Na+/K+-ATPase alpha1-beta1 and alpha1-beta2 isozymes, which are preferentially expressed in different regions of the inner ear and also with gastric and non-gastric H+/K+-ATPase.

Subcellular location: Extracellular


Synonyms: FXYD domain containing ion transport regulator 6, FXYD domain containing ion transport regulator 6 precursor, Phosphohippolin, UNQ521/PRO1056, FXYD6_HUMAN.
ID gène 53826
Indications d'application FCM(1:20-100)
Commentaires

Exitation/Emission: 480,565nm/578nm

Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months