anthrax Toxin Receptor 1 (ANTXR1) anticorps (PE)

Détails pour le produit réf. ABIN1712698, Fournisseur: Connectez-vous pour afficher
Antigène
  • ANTXR1
  • ATR
  • TEM8
  • 2310008J16Rik
  • 2810405N18Rik
  • Antrx1
  • Tem8
  • anthrax toxin receptor 1
  • ANTXR1
  • LOC100357637
  • Antxr1
Reactivité
Humain, Souris, Rat (Rattus)
172
62
58
4
4
3
3
2
2
2
2
1
1
Hôte
Lapin
133
24
17
Clonalité
Polyclonal
Conjugué
PE
10
10
10
8
7
7
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
101
76
49
34
34
26
22
22
5
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human TEM8
Isotype IgG
Purification Purified by Protein A.
Autre désignation Tem8 (ANTXR1 Antibody Extrait)
Sujet

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]

Subcellular location: Extracellular


Synonyms: Anthrax toxin receptor 1, Anthrax toxin receptor 1 precursor, ANTXR 1, ANTXR1, ATR, TEM-8, TEM 8, TEM8, Tumor Endothelial Marker 8, Tumor endothelial marker 8 precursor, ANTR1_HUMAN, Anthrax toxin receptor-1, FLJ11298, FLJ21776.
Domaine de recherche Cardiovascular, Angiogenesis
Indications d'application FCM(1:20-100)
Commentaires

Exitation/Emission: 480,565nm/578nm

Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months