Cell Adhesion Molecule-Related/down-Regulated By Oncogenes (CDON) anticorps (PE)

Détails pour le produit réf. ABIN1712743, Fournisseur: Connectez-vous pour afficher
Antigène
  • cb507
  • wu:fa10c03
  • wu:fb94b11
  • zgc:158240
  • CDO
  • CDON1
  • HPE11
  • ORCAM
  • Cdo
  • cdon-A
  • Cd0
  • Orcam
  • cell adhesion molecule-related/down-regulated by oncogenes
  • Cdon homolog (mouse)
  • cell adhesion associated, oncogene regulated
  • cysteine dioxygenase, type I
  • cdon
  • CDON
  • Cdon
  • CDO1
Reactivité
Humain, Souris, Rat (Rattus)
54
21
19
4
3
1
1
Hôte
Lapin
32
13
7
2
2
Clonalité
Polyclonal
Conjugué
PE
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
31
18
13
6
6
3
2
2
2
1
1
Options
Fournisseur
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Supplier Product No.
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Immunogène KLH conjugated synthetic peptide derived from human CDON
Isotype IgG
Purification Purified by Protein A.
Autre désignation Cdon (CDON Antibody Extrait)
Sujet

Cell adhesion molecule-related/down-regulated by oncogenes (CDO) and BOC (brother of CDO) are members of the immunoglobulin/fibronectin type III repeat family and act as cell surface receptors. CDO is a component of a cell-surface receptor complex which also contains BOC, NEO1, CTNNB1 and cadherins and which acts as a mediator of cell-cell interactions between muscle cells. CDO and BOC are single pass membrane proteins that play a role in myogenic cell differentiation. Together, CDO and BOC participate in a positive feedback loop with MyoD, a myogenic transcription factor. The 1,242 amino acid rat CDO protein has a 24 residue signal sequence, five Ig V-like repeats, a 25 residue membrane-spanning region, three FNIII-like repeats and a cytoplasmic region of 256 amino acids containing a proline-rich stretch. The human protein contains 1,225 amino acid residues and shares significant homology with the domain structures of the rat protein.

Subcellular location: Extracellular


Synonyms: CDO, CDON, Cell adhesion molecule-related/down-regulated by oncogenes, CDON_HUMAN.
ID gène 50937
Pathways Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Embryonic Body Morphogenesis
Indications d'application FCM(1:20-100)
Commentaires

Exitation/Emission: 480,565nm/578nm

Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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