G Protein-Coupled Receptor 12 anticorps (GPR12) (PE)

Details for Product anti-GPR12 Antibody No. ABIN1712767, Fournisseur: Connectez-vous pour afficher
Antigène
  • GPCR12
  • GPCR21
  • Gpcr12
  • Gpcr01
  • Gpcr20
  • Gpcr21
  • G protein-coupled receptor 12
  • G-protein coupled receptor 12
  • GPR12
  • Gpr12
Reactivité
Humain, Souris, Rat (Rattus)
74
48
46
7
6
6
5
5
4
3
2
1
1
1
1
Hôte
Lapin
74
Clonalité
Polyclonal
Conjugué
Cet anticorp G Protein-Coupled Receptor 12 est conjugé à/à la PE
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Flow Cytometry (FACS)
26
25
24
12
8
6
2
2
1
Options
Fournisseur
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Immunogène KLH conjugated synthetic peptide derived from human G protein coupled receptor 12
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gpr12 (GPR12 Antibody Extrait)
Sujet

G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR12 is a 334 amino acid peptide that is expressed primarily in brain, particularly in regions where neuronal differentiation takes place. GPR12 is coupled to an inhibitory G protein. It positively influences differentiation and maturation of post-mitotic neurons, and it may promote the growth of neuronal precursor cells.

Subcellular location: Extracellular


Synonyms: FLJ18149, FLJ97704, G protein coupled receptor 12, G-protein coupled receptor 12, GPCR12, GPCR21, GPR 12, GPR12, GPR12_HUMAN, MGC138349, MGC138351, Probable G protein coupled receptor GPR12, GPCR GPR12.
ID gène 2835
Indications d'application FCM(1:20-100)
Commentaires

Exitation/Emission: 480,565nm/578nm

Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months