MAP2K4 anticorps

N° du produit ABIN1724655

Détail du produit anti-MAP2K4 anticorps

Antigène: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAP2K4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Purification: purified

Immunogène: Purified recombinant fragment of MAP2K4 expressed in E. coli.

Clone: 2D10D8

Isotype: IgM

Information d'application

Indications d'application: ELISA: 1:10000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-MAP2K4 (ABIN1724655)

Kim, Vander Griend, Yang, Benson, Dubauskas, Yoshida, Chekmareva, Ichikawa, Sokoloff, Zhan, Karrison, Lin, Stadler, Ichikawa, Rubin, Rinker-Schaeffer: "Mitogen-activated protein kinase kinase 4 metastasis suppressor gene expression is inversely related to histological pattern in advancing human prostatic cancers." dans: Cancer research, Vol. 61, Issue 7, pp. 2833-7, (2001) (PubMed).

Cuenda: "Mitogen-activated protein kinase kinase 4 (MKK4)." dans: The international journal of biochemistry & cell biology, Vol. 32, Issue 6, pp. 581-7, (2000) (PubMed).

Détails sur MAP2K4

Antigène: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Autre désignation: MAP2K4 (MAP2K4 Produits)

Synonymes: anticorps JNKK, anticorps JNKK1, anticorps MAPKK4, anticorps MEK4, anticorps MKK4, anticorps PRKMK4, anticorps SAPKK-1, anticorps SAPKK1, anticorps SEK1, anticorps SERK1, anticorps SKK1, anticorps Sek1, anticorps Serk1, anticorps MKK4A-l, anticorps map2k4, anticorps zgc:136500, anticorps jnkk, anticorps mek4, anticorps mkk4, anticorps sek1, anticorps jnkk1, anticorps serk1, anticorps xmek2, anticorps mapkk4, anticorps prkmk4, anticorps 142758_at, anticorps CG9738, anticorps CT27508, anticorps D-MKK4, anticorps DMKK4, anticorps Dmel\\CG9738, anticorps JNKK2, anticorps Mpk4, anticorps SEK1/MKK4, anticorps dMKK4, anticorps dMkk4, anticorps hep, anticorps ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4, anticorps ATMEK4, anticorps ATMKK4, anticorps F19C24.26, anticorps F19C24_26, anticorps MAP KINASE KINASE 4, anticorps mitogen-activated protein kinase kinase 4, anticorps MKK4B, anticorps zgc:194486, anticorps mitogen-activated protein kinase kinase 4, anticorps mitogen-activated protein kinase kinase 4a, anticorps MAP kinase kinase 4, anticorps mitogen activated protein kinase kinase 4, anticorps mitogen-activated protein kinase kinase 4b, anticorps MAP2K4, anticorps Map2k4, anticorps map2k4a, anticorps map2k4, anticorps Mkk4, anticorps MKK4, anticorps map2k4b

Sujet:

Description: MAP2K4(mitogen-activated protein kinase kinase 4), which is located on chromosome 17p11.2, with 399-amino acid protein (about 45 kDa), belongs to the family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. MEK-4 (also called MEK4/MKK4) activates both p38 and JNK MAP kinases. MKK4 is a central mediator in the stress activated protein kinase signaling pathway that responds to a number of cellular and environmental stressors. By phosphorylating MAP kinases such as JNK,MKK4 can ultimately transmit stress signals to nuclear transcription factors that mediate various processes including proliferation, apoptosis, and differentiation. Its distinct biological functions have been identified for MKK4 including a role in development, hepatogenesis, and metastasis suppression.

Aliases: MAP2K4

ID gène: 6416

HGNC: 6416

Pathways: Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling