Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CSF1R anticorps (AA 344-497)

CSF1R Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Souris Monoclonal 6B9H2 unconjugated
N° du produit ABIN1724928
  • Antigène Voir toutes CSF1R Anticorps
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    Épitope
    • 20
    • 20
    • 18
    • 16
    • 16
    • 15
    • 14
    • 11
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 344-497
    Reactivité
    • 196
    • 140
    • 97
    • 17
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 224
    • 30
    • 8
    • 3
    • 2
    Souris
    Clonalité
    • 226
    • 40
    • 1
    Monoclonal
    Conjugué
    • 94
    • 27
    • 15
    • 15
    • 14
    • 11
    • 10
    • 10
    • 9
    • 9
    • 9
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CSF1R est non-conjugé
    Application
    • 174
    • 106
    • 88
    • 67
    • 50
    • 26
    • 24
    • 21
    • 12
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human CSF1R (AA: 344-497) expressed in E. coli.
    Clone
    6B9H2
    Isotype
    IgG2b
    Top Product
    Discover our top product CSF1R Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Morandi, Barbetti, Riverso, Dello Sbarba, Rovida: "The colony-stimulating factor-1 (CSF-1) receptor sustains ERK1/2 activation and proliferation in breast cancer cell lines." dans: PLoS ONE, Vol. 6, Issue 11, pp. e27450, (2011) (PubMed).

    Kitagawa, Gouda, Kirii, Sugiyama, Ishihama, Fujii, Narumi, Akita, Yokota: "Characterization of kinase inhibitors using different phosphorylation states of colony stimulating factor-1 receptor tyrosine kinase." dans: Journal of biochemistry, Vol. 151, Issue 1, pp. 47-55, (2011) (PubMed).

  • Antigène
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    Autre désignation
    CSF1R (CSF1R Produits)
    Synonymes
    anticorps AI323359, anticorps CD115, anticorps CSF-1R, anticorps Csfmr, anticorps Fim-2, anticorps Fms, anticorps M-CSF-R, anticorps M-CSFR, anticorps C-FMS, anticorps CSFR, anticorps FIM2, anticorps FMS, anticorps HDLS, anticorps PDGFRB, anticorps MGC89146, anticorps CSF-1-R, anticorps c-fms, anticorps mrfms, anticorps CSF1, anticorps M-CSF, anticorps csf1r, anticorps fms, anticorps panther, anticorps colony stimulating factor 1 receptor, anticorps macrophage colony-stimulating factor receptor, anticorps colony stimulating factor 1 receptor, a, anticorps Csf1r, anticorps CSF1R, anticorps m-csfr, anticorps csf1r, anticorps csf1ra
    Sujet

    Description: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. ,

    Aliases: FMS, CSFR, FIM2, HDLS, C-FMS, CD115, CSF-1R, M-CSF-R

    Poids moléculaire
    108 kDa
    ID gène
    1436
    HGNC
    1436
    Pathways
    Signalisation RTK, Inositol Metabolic Process, Cell-Cell Junction Organization
Vous êtes ici:
Support technique