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CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) (AA 202-216) anticorps

Détails pour le produit réf. ABIN181099, Fournisseur: Connectez-vous pour afficher
Antigène
  • CD79A
  • Ig-alpha
  • Iga
  • Igalpha
  • Ly-54
  • Ly54
  • mb-1
  • IGA
  • MB-1
  • IG-alpha
Épitope
AA 202-216
49
38
23
16
15
15
10
9
5
4
3
3
3
3
2
2
1
1
1
1
1
1
1
Reactivité
Poulet, Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Singe, Souris, Porc, Lapin, Rat (Rattus)
252
81
42
38
37
31
29
29
26
20
16
9
6
3
3
3
3
3
3
2
Hôte
Souris
169
112
4
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Inconjugué
26
26
15
13
7
5
2
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
131
121
69
62
53
23
23
19
6
4
4
4
3
2
2
1
1
1
1
Fournisseur
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Immunogène Synthetic peptide corresponding to 202-216 amino acid sequence of Human mb-1. Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cellline. Genename: CD79a
Clone HM57
Isotype IgG1
Specificité This antibody recognizes an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45 kDa protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells.
Attributs du produit Synonyms: IGA, MB1, B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain,MB-1 membrane glycoprotein, Surface IgM-associated protein, Membrane-boundimmunoglobulin-associated protein
Purification Affinity Chromatography on Protein G
Autre désignation CD79a (CD79A Antibody Extrait)
Sujet The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein
ID gène 973
UniProt P11912
Domaine de recherche Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells
Pathways
Indications d'application Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/100-1/500, This product requires antigenretrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Recommended Positive Control: Human tonsilFlow Cytometry: Use 10 μL of 1/50-1/100 diluted CD79a antibody to label 1x10^6 cells in 100μL (Membrane permeabilisation is required). Has been reported to work in Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Date de péremption 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) (AA 202-216) anticorps (ABIN181099) anti-CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) (AA 202-216) antibody
Reference: Background Jones, Cordell, Beyers et al.: "Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 12, pp. 5429-35, 1993 (PubMed).

Mason, Cordell, Tse et al.: "The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 11, pp. 2474-82, 1991 (PubMed).