CD11c anticorps (Internal Region)

N° du produit ABIN181257

Détail du produit anti-CD11c anticorps

Antigène: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD11c est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody recognises Integrin Alpha X, Family: Integrin, Subfamily: not assigned-Integrin.

Réactivité croisée (Details): Species reactivity (expected):Gorilla, GibbonSpecies reactivity (tested):Human

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic 14 amino acid peptide from internal region of Human ITGAX / CD11c.

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Embedded Tissues (20 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Détails sur CD11c

Antigène: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Autre désignation: CD11c (ITGAX Produits)

Synonymes: anticorps CD11C, anticorps SLEB6, anticorps RGD1561123, anticorps AI449405, anticorps Cd11c, anticorps Cr4, anticorps N418, anticorps integrin subunit alpha X, anticorps integrin alpha X, anticorps ITGAX, anticorps Itgax

Sujet: CD11c / ITGAX encodes the integrin alpha X chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 seems to broadly overlap the properties of the alpha M beta 2 integrin in adherence of neutrophils and monocytes to stimulated endothelium, and the phagocytosis of complement coated particles.Synonyms: CD11 antigen-like family member C, ITGAX, Integrin alpha-X, Leu M5, Leukocyte adhesion glycoprotein p150 95 alpha chain, Leukocyte adhesion receptor p150 95

ID gène: 3687

NCBI Accession: NP_000878

UniProt: P20702

Pathways: Système du Complément, Activated T Cell Proliferation, Integrin Complex