TADA3L anticorps (Middle Region)

N° du produit ABIN182375

Détail du produit anti-TADA3L anticorps

Antigène: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TADA3L est non-conjugé

Application: Western Blotting (WB)

Séquence: ASVEPYCADI TSEEVRTLEE LLKPPEDEAE HYKIPPLGKH YSQRWAQEDL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TADA3L. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TADA3L

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 432 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TADA3L

Antigène: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Autre désignation: TADA3L (TADA3 Produits)

Synonymes: anticorps ADA3, anticorps NGG1, anticorps STAF54, anticorps TADA3L, anticorps hADA3, anticorps Tada3l, anticorps 1110004B19Rik, anticorps AI987856, anticorps fa03f04, anticorps tada3, anticorps wu:fa03f04, anticorps zgc:63596, anticorps ada3, anticorps ada3-A, anticorps ngg1, anticorps tada3l, anticorps tada3l-a, anticorps ada3-B, anticorps tada3l-B, anticorps transcriptional adaptor 3, anticorps transcriptional adapter 3 pseudogene, anticorps transcriptional adaptor 3 (NGG1 homolog, yeast)-like, anticorps transcriptional adaptor 3 L homeolog, anticorps transcriptional adaptor 3 S homeolog, anticorps TADA3, anticorps Tada3, anticorps LOC732883, anticorps LOC100061462, anticorps tada3, anticorps LOC100619707, anticorps tada3l, anticorps tada3.L, anticorps tada3.S

Sujet: Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: ADA3, FLJ20221, FLJ21329, hADA3, NGG1, TADA3L
Protein Interaction Partner: HEXIM2, CCDC101, CCNC, TP53, USP22, KDM1A, TADA2A, KAT2B, TAF5L, NUP205, SUPT3H, YEATS2, MBIP, WDR5, MAP3K7, DR1, PIAS4, MAGEH1, ING5, XRCC6, SUMO2, SREBF1, TXNRD2, NR1I2, RARA, ESR1, AR, KAT2A, EP300, CTNNB1, ANKRD12, ATXN7, TAF10, FAM107B, ADPGK, HSPA8,
Protein Size: 432

Poids moléculaire: 49 kDa

ID gène: 10474

NCBI Accession: NM_006354, NP_006345

UniProt: O75528

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway