FOXA3 anticorps (Middle Region)

N° du produit ABIN182452

Détail du produit anti-FOXA3 anticorps

Antigène: FOXA3 (Forkhead Box A3 (FOXA3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: FENGCYLRRQ KRFKLEEKVK KGGSGAATTT RNGTGSAAST TTPAATVTSP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against FOXA3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FOXA3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 350 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FOXA3 (ABIN182452)

Menga, Infantino, Iacobazzi, Convertini, Palmieri, Iacobazzi: "Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier." dans: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 23, Issue 8, pp. 978-87, (2013) (PubMed).

Détails sur FOXA3

Antigène: FOXA3 (Forkhead Box A3 (FOXA3))

Autre désignation: FOXA3 (FOXA3 Produits)

Synonymes: anticorps FOXA3, anticorps Zffkh1, anticorps fa11c04, anticorps fkd2, anticorps forkhead-2, anticorps wu:fa11c04, anticorps wu:fc37a08, anticorps zf-FKH1, anticorps FKHH3, anticorps HNF3G, anticorps TCF3G, anticorps HNF3-G, anticorps Hnf-3g, anticorps Hnf3g, anticorps Tcf-3g, anticorps Tcf3g, anticorps forkhead box A3, anticorps FOXA3, anticorps foxa3, anticorps Foxa3

Sujet: FOXA3 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved.
Alias Symbols: FKHH3, HNF3G, TCF3G
Protein Interaction Partner: PPARA, ALX4, TLE2, TLE1, HMGB1,
Protein Size: 350

Poids moléculaire: 37 kDa

ID gène: 3171

NCBI Accession: NM_004497, NP_004488

UniProt: P55318

Pathways: Carbohydrate Homeostasis