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SMAD7 anticorps (N-Term)

SMAD7 Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN182475
  • Antigène Voir toutes SMAD7 Anticorps
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Épitope
    • 17
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 46
    • 26
    • 24
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Porc, Boeuf (Vache), Chien, Lapin
    Hôte
    • 39
    • 7
    Lapin
    Clonalité
    • 40
    • 6
    Polyclonal
    Conjugué
    • 29
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SMAD7 est non-conjugé
    Application
    • 26
    • 17
    • 14
    • 14
    • 10
    • 8
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    EEEGAGGGGG GGELRGEGAT DSRAHGAGGG GPGRAGCCLG KAVRGAKGHH
    Homologie
    Cow: 93%, Dog: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 85%
    Attributs du produit
    This is a rabbit polyclonal antibody against SMAD7. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD7
    Top Product
    Discover our top product SMAD7 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 426 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Autre désignation
    SMAD7 (SMAD7 Produits)
    Synonymes
    anticorps CRCS3, anticorps MADH7, anticorps MADH8, anticorps Smad7a, anticorps Madh7, anticorps Smad10, anticorps madh7, anticorps xsmad7, anticorps wu:fj60c10, anticorps SMAD family member 7, anticorps SMAD family member 7 L homeolog, anticorps SMAD7, anticorps Smad7, anticorps smad7.L, anticorps smad7
    Sujet
    Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
    Alias Symbols: CRCS3, MADH7, MADH8
    Protein Interaction Partner: HDAC3, HDAC2, USP11, SMURF2, SMURF1, SKP2, MYC, Melk, HCVgp1, RNF111, KDM2A, SOX13, PIAS1, SOX7, UBE2O, MKL2, ASH1L, PIAS4, CXXC5, ZNF107, ZBTB11, HEYL, TTF2, UBC, TTF1, SOX5, MYOD1, XRCC6, CTNNB1, MAPK14, BAMBI, PPP1R15A, NEDD4L, STAMBP, YAP1, AXIN1, TP5
    Protein Size: 426
    Poids moléculaire
    46 kDa
    ID gène
    4092
    NCBI Accession
    NM_005904, NP_005895
    UniProt
    O15105
    Pathways
    Interferon-gamma Pathway, Cell-Cell Junction Organization
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