RRN3 anticorps (Middle Region)

N° du produit ABIN183013

Détail du produit anti-RRN3 anticorps

Antigène: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRN3 est non-conjugé

Application: Western Blotting (WB)

Séquence: VDGKVDNGKT KDLYRDLINI FDKLLLPTHA SCHVQFFMFY LCSFKLGFAE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RRN3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RRN3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 650 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RRN3

Antigène: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Autre désignation: RRN3 (RRN3 Produits)

Synonymes: anticorps RRN3, anticorps DKFZp459B073, anticorps CG16938, anticorps CG3278, anticorps CG5951, anticorps Dmel\\CG3278, anticorps TIF-1A, anticorps TIF-IA, anticorps Tif-1A, anticorps TifIA, anticorps dTIF-IA, anticorps dyak_GLEANR_13182, anticorps DyakGE12956, anticorps GE12956, anticorps Tif-IA, anticorps A-270G1.2, anticorps TIFIA, anticorps RGD1305001, anticorps AL023001, anticorps E130302O19Rik, anticorps R75565, anticorps Tif1a, anticorps RRN3 homolog, RNA polymerase I transcription factor, anticorps RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae), anticorps CG3278 gene product from transcript CG3278-RA, anticorps GE12956 gene product from transcript GE12956-RA, anticorps RRN3 homolog, RNA polymerase I transcription factor L homeolog, anticorps RRN3 RNA polymerase I transcription factor homolog (yeast), anticorps RRN3, anticorps rrn3, anticorps Tif-IA, anticorps Dyak\Tif-IA, anticorps rrn3.L, anticorps Rrn3

Sujet: In mammals, growth-dependent regulation of RNA polymerase I (Pol I) transcription is mediated by RRN3, an essential initiation factor. It interacts with Pol I in the absence of template DNA, augments Pol I transcription in vivo and rescues transcription in extracts from growth-arrested cells in vitro.
Alias Symbols: TIFIA, A-270G1.2
Protein Interaction Partner: UBC, ACTA1, Polr1e, POLR1B, EIF3L, NMI, RBM15, UBD, Trim28, ELAVL1, TAF1D, POLR1A, MYO1C, TAF1C, TAF1B, TAF1A, UBTF, TBP, PPP2R2A, CDK2, CCNE1, RIBIN, ACTB,
Protein Size: 650

Poids moléculaire: 74 kDa

ID gène: 54700

NCBI Accession: NM_018427, NP_060897

UniProt: Q9NYV6

Pathways: Negative Regulation of intrinsic apoptotic Signaling