CATSPER2 anticorps (N-Term)

N° du produit ABIN183176

Détail du produit anti-CATSPER2 anticorps

Antigène: CATSPER2 (Cation Channel, Sperm Associated 2 (CATSPER2))

Épitope: N-Term

Reactivité: Humain, Lapin, Boeuf (Vache), Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CATSPER2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: HLQGLSQAVP RHTIRELLDP SRQKKLVLGD QHQLVRFSIK PQRIEQISHA

Homologie: Cow: 85%, Horse: 92%, Human: 100%, Pig: 92%, Rabbit: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CATSPER2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CATSPER2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 414 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CATSPER2 (ABIN183176)

Kawano, Araki, Yoshida, Hibino, Ohnami, Makino, Kanai, Hasuwa, Yoshida, Miyado, Umezawa: "Seminal vesicle protein SVS2 is required for sperm survival in the uterus." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 11, pp. 4145-50, (2014) (PubMed).

Détails sur CATSPER2

Antigène: CATSPER2 (Cation Channel, Sperm Associated 2 (CATSPER2))

Autre désignation: CATSPER2 (CATSPER2 Produits)

Synonymes: anticorps CATSPER2, anticorps cation channel, sperm associated 2, anticorps cation channel sperm associated 2, anticorps CATSPER2, anticorps Catsper2

Sujet: Calcium ions play a primary role in the regulation of sperm motility. Anti-CATSPER2 belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. A second, closely linked copy of this gene has been identified. Although multiple transcript variants encoding protein isoforms have been characterized, they seem to be only transcribed from this gene. Additional splice variants have been described but their full-length nature has not been determined.
Protein Size: 414

Poids moléculaire: 46 kDa

ID gène: 117155

NCBI Accession: NM_172096, NP_742094

UniProt: Q96P54