T-Bet anticorps (C-Term)

N° du produit ABIN183466

Détail du produit anti-T-Bet anticorps

Antigène: T-Bet

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp T-Bet est non-conjugé

Application: Western Blotting (WB)

Séquence: MDPGLGSSEE QGSSPSLWPE VTSLQPESSD SGLGEGDTKR RRISPYPSSG

Homologie: Cow: 86%, Dog: 86%, Human: 93%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TBX21. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of mouse TBX21

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 530 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur T-Bet

Antigène: T-Bet

Autre désignation: TBX21 (T-Bet Produits)

Synonymes: anticorps T-PET, anticorps T-bet, anticorps TBET, anticorps TBLYM, anticorps TBT1, anticorps Tbet, anticorps Tblym, anticorps T-box 21, anticorps TBX21, anticorps Tbx21

Sujet: TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Alias Symbols: TBT1, Tbet, Tblym
Protein Interaction Partner: Bcl6, Smarca4, Tlx3, Tead4, Pax9, Gsc, Gata3, Dlx1, Alx4, Rbpj, Stat1, Ifng, Tec, Itk, Txk,
Protein Size: 530

Poids moléculaire: 58 kDa

ID gène: 57765

NCBI Accession: NM_019507, NP_062380

UniProt: Q9JKD8