ISL2 anticorps (C-Term)

N° du produit ABIN183487

Détail du produit anti-ISL2 anticorps

Antigène: ISL2 (ISL LIM Homeobox 2 (ISL2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Cobaye, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISL2 est non-conjugé

Application: Western Blotting (WB)

Séquence: VIRVWFQNKR CKDKKKSILM KQLQQQQHSD KASFQGLTGT PLVAGSPIGH

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 86%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ISL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of mouse ISL2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 359 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ISL2 (ABIN183487)

Svärd, Heby-Henricson, Henricson, Persson-Lek, Rozell, Lauth, Bergström, Ericson, Toftgård, Teglund: "Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway." dans: Developmental cell, Vol. 10, Issue 2, pp. 187-97, (2006) (PubMed).

Détails sur ISL2

Antigène: ISL2 (ISL LIM Homeobox 2 (ISL2))

Autre désignation: ISL2 (ISL2 Produits)

Synonymes: anticorps ISL-2, anticorps isl2, anticorps wu:fc29g02, anticorps zfIsl-2, anticorps ISLET-2, anticorps ISL-3, anticorps isl3, anticorps islet 3, anticorps zfIsl-3, anticorps zgc:109840, anticorps ISL LIM homeobox 2, anticorps ISL LIM homeobox 2a, anticorps ISL LIM homeobox 2b, anticorps ISL2, anticorps Isl2, anticorps isl2a, anticorps isl2b

Sujet: Isl2 specifies RGC laterality by repressing an ipsilateral pathfinding program unique to VTC RGCs and involving Zic2 and EphB1. This genetic hierarchy controls binocular vision.
Alias Symbols: 3110001N10Rik
Protein Interaction Partner: Zfp446, Ssbp4, Ssbp3, Pygo1, Ssbp2, Lhx4, Ldb2, Ldb1,
Protein Size: 359

Poids moléculaire: 39 kDa

ID gène: 104360

NCBI Accession: NM_027397, NP_081673

UniProt: Q9CXV0