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MECOM anticorps (N-Term)

MECOM Reactivité: Humain, Souris, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN183666
  • Antigène Voir toutes MECOM Anticorps
    MECOM (MDS1 and EVI1 Complex Locus (MECOM))
    Épitope
    • 17
    • 14
    • 9
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 62
    • 24
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Poisson zèbre (Danio rerio)
    Hôte
    • 56
    • 13
    • 1
    Lapin
    Clonalité
    • 59
    • 11
    Polyclonal
    Conjugué
    • 35
    • 7
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MECOM est non-conjugé
    Application
    • 55
    • 43
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MRSKGRARKL ATNNECVYGN YPEIPLEEMP DADGVASTPS LNIQEPCSPA
    Homologie
    Human: 100%, Mouse: 93%, Zebrafish: 77%
    Attributs du produit
    This is a rabbit polyclonal antibody against MDS1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human MDS1
    Top Product
    Discover our top product MECOM Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 169 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    MECOM (MDS1 and EVI1 Complex Locus (MECOM))
    Autre désignation
    MDS1 (MECOM Produits)
    Synonymes
    anticorps AML1-EVI-1, anticorps EVI1, anticorps MDS1, anticorps MDS1-EVI1, anticorps PRDM3, anticorps D630039M04Rik, anticorps Evi-1, anticorps Evi1, anticorps Jbo, anticorps Mds, anticorps Mds1, anticorps Mds1-Evi1, anticorps Prdm3, anticorps Znfpr1b1, anticorps evi1, anticorps im:7140716, anticorps prdm3, anticorps evi-1, anticorps mecom, anticorps mecom-a, anticorps mecom-b, anticorps xEvi-1, anticorps evi1-B, anticorps MDS1 and EVI1 complex locus, anticorps MDS1 and EVI1 complex locus L homeolog, anticorps MDS1 and EVI1 complex locus S homeolog, anticorps MECOM, anticorps Mecom, anticorps mecom, anticorps mecom.L, anticorps mecom.S
    Sujet
    MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon(s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3,21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.
    Alias Symbols: PRDM3, MDS1-EVI1
    Protein Size: 169
    Poids moléculaire
    19 kDa
    ID gène
    4197
    NCBI Accession
    NM_004991, NP_004982
    UniProt
    Q13465
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