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DMAP1 anticorps (C-Term)

DMAP1 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN183792
  • Antigène Voir toutes DMAP1 Anticorps
    DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
    Épitope
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 34
    • 13
    • 10
    • 9
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Poisson zèbre (Danio rerio)
    Hôte
    • 27
    • 4
    • 4
    Lapin
    Clonalité
    • 31
    • 4
    Polyclonal
    Conjugué
    • 26
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DMAP1 est non-conjugé
    Application
    • 25
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    PGPASAEPAV TEPGLGPDPK DTIIDVVGAP LTPNSRKRRE SASSSSSVKK
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against DMAP1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human DMAP1
    Top Product
    Discover our top product DMAP1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 467 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
    Autre désignation
    DMAP1 (DMAP1 Produits)
    Synonymes
    anticorps Afu4g07380, anticorps T8I13.5, anticorps DNMAP1, anticorps DNMTAP1, anticorps EAF2, anticorps MEAF2, anticorps SWC4, anticorps zgc:55593, anticorps dnmap1, anticorps dnmtap1, anticorps eaf2, anticorps meaf2, anticorps swc4, anticorps 1500016M21Rik, anticorps Dmtap1, anticorps mKIAA1425, anticorps DNA methyltransferase 1-associated protein DMAP1, anticorps DNA methyltransferase 1-associated protein 1, anticorps DNA methyltransferase 1 associated protein 1, anticorps myb-like transcription factor family protein, anticorps DNA methyltransferase 1 associated protein 1 L homeolog, anticorps AFUA_4G07380, anticorps NFIA_108840, anticorps ACLA_046700, anticorps CpipJ_CPIJ017959, anticorps Bm1_47540, anticorps PMAA_026820, anticorps AFLA_112450, anticorps TSTA_072020, anticorps BDBG_02603, anticorps AT2G47210, anticorps CpipJ_CPIJ007438, anticorps DMAP1, anticorps dmap1, anticorps dmap1.L, anticorps Dmap1
    Sujet
    DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
    Alias Symbols: EAF2, SWC4, MEAF2, DNMAP1, DNMTAP1
    Protein Interaction Partner: SOX2, UBC, RNF2, HECW2, RUVBL2, SRCAP, CFDP1, RUVBL1, DENR, VPS72, TOMM34, TSG101, H2AFZ, DAXX, SMARCAD1, SUMO2, EPC1, ACTL6A, ACTA1, PPP2R2D, ING3, MORF4L1, BRD8, KAT5, TRRAP, YEATS4, EP400, EPC2, MYC, MAX, ACTG1, ACTB, MRGBP, MORF4L2, MNAT1, HDAC1, tat,
    Protein Size: 467
    Poids moléculaire
    53 kDa
    ID gène
    55929
    NCBI Accession
    NM_019100, NP_061973
    UniProt
    Q9NPF5
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