YARS anticorps (C-Term)

N° du produit ABIN183962

Détail du produit anti-YARS anticorps

Antigène: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio), Chévre, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YARS est non-conjugé

Application: Western Blotting (WB)

Séquence: QVEPLDPPAG SAPGEHVFVK GYEKGQPDEE LKPKKKVFEK LQADFKISEE

Homologie: Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against YARS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human YARS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 528 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur YARS

Antigène: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Autre désignation: YARS (Yars Produits)

Synonymes: anticorps CMTDIC, anticorps TYRRS, anticorps YRS, anticorps YTS, anticorps AL024047, anticorps AU018965, anticorps cb204, anticorps wu:fk52b08, anticorps YARS, anticorps cmtdic, anticorps tyrrs, anticorps yrs, anticorps yts, anticorps CG4561, anticorps Dmel\\CG4561, anticorps TyrRS, anticorps anon-EST:Posey261, anticorps dYARS, anticorps GB10789, anticorps tyrosyl-tRNA synthetase, anticorps tyrosyl-tRNA synthetase L homeolog, anticorps tyrosyl-tRNA synthetase, putative, anticorps tyrosine--tRNA ligase, anticorps Tyrosyl-tRNA synthetase, anticorps tyrosine--tRNA ligase, cytoplasmic, anticorps YARS, anticorps Yars, anticorps yars, anticorps yars.L, anticorps MAL8P1.125, anticorps MEFER_RS04475, anticorps TyrRS, anticorps LOC413909, anticorps LOC100163888, anticorps LOC100282315

Sujet: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
Alias Symbols: YRS, YTS, TYRRS, CMTDIC
Protein Interaction Partner: UBC, SARNP, NRD1, HSPA8, VCAM1, ITGA4, FN1, METTL16, XRCC5, DYNC1H1, CDK2, ELANE, EIF1B, SAP18, EIF6, ARF6,
Protein Size: 528

Poids moléculaire: 58 kDa

ID gène: 8565

NCBI Accession: NM_003680, NP_003671

UniProt: P54577