TIAL1 anticorps (C-Term)

N° du produit ABIN184155

Détail du produit anti-TIAL1 anticorps

Antigène: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cheval, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIAL1 est non-conjugé

Application: Western Blotting (WB)

Séquence: WNQQGFGVDQ SPSAAWMGGF GAQPPQGQAP PPVIPPPNQA GYGMASYQTQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%, Zebrafish: 76%

Attributs du produit: This is a rabbit polyclonal antibody against TIAL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TIAL1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 375 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TIAL1

Antigène: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Autre désignation: TIAL1 (TIAL1 Produits)

Synonymes: anticorps TCBP, anticorps TIAR, anticorps 5330433G13Rik, anticorps AL033329, anticorps mTIAR, anticorps zgc:66130, anticorps tcbp, anticorps tiar, anticorps TIA1 cytotoxic granule associated RNA binding protein like 1, anticorps Tia1 cytotoxic granule-associated RNA binding protein-like 1, anticorps TIA1 cytotoxic granule-associated RNA binding protein-like 1, anticorps TIAL1, anticorps Tial1, anticorps tial1

Sujet: The protein encoded by TIAL1 is a member of a family of RNA-binding proteins and possesses nucleolytic activity against cytotoxic lymphocyte target cells. The gene product is a cytotoxic granule-associated protein and has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. It has been suggested that members of this protein family may be involved in the induction of apoptosis. One isoform contains a lysosome-targeting motif in its C-terminal auxiliary domain, however, alternative splicing results in a T-cluster DNA-binding isoform, differing at the C-terminus where a hydrophobic sequence replaces the lysosome-targeting motif.
Alias Symbols: TCBP, TIAR
Protein Interaction Partner: SUMO2, UBC, RPA3, RPA2, RPA1, BMI1, SOX2, MAPK1, GADD45A, VCAM1, ITGA4, FN1, MRPL53, SARNP, UFM1, SBDS, MRPS28, TOMM40, ACAA2, GNB2L1, SF3B4, SCAMP3, SCO2, ALDH5A1, VDAC1, UBE2D2, THY1, SOD1, MBNL1, CAND1, DCUN1D1, COPS5, COPS6, CUL1, CUL2, CUL3, CUL4A, C
Protein Size: 375

Poids moléculaire: 42 kDa

ID gène: 7073

NCBI Accession: NM_003252, NP_003243

UniProt: Q01085