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Serotonin Receptor 1A anticorps (N-Term)

HTR1A Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN184237
  • Antigène Voir toutes Serotonin Receptor 1A (HTR1A) Anticorps
    Serotonin Receptor 1A (HTR1A)
    Épitope
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 43
    • 27
    • 27
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 37
    • 5
    • 2
    Lapin
    Clonalité
    • 40
    • 4
    Polyclonal
    Conjugué
    • 24
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Serotonin Receptor 1A est non-conjugé
    Application
    • 34
    • 18
    • 14
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    GQGNNTTSPP APFETGGNTT GISDVTVSYQ VITSLLLGTL IFCAVLGNAC
    Homologie
    Human: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against HTR1A. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human HTR1A
    Top Product
    Discover our top product HTR1A Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 422 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Adeosun, Albert, Austin, Iyo: "17?-estradiol-induced regulation of the novel 5-HT1A-related transcription factors NUDR and Freud-1 in SH SY5Y cells." dans: Cellular and molecular neurobiology, Vol. 32, Issue 4, pp. 517-21, (2012) (PubMed).

    Szewczyk, Albert, Rogaeva, Fitzgibbon, May, Rajkowska, Miguel-Hidalgo, Stockmeier, Woolverton, Kyle, Wang, Austin: "Decreased expression of Freud-1/CC2D1A, a transcriptional repressor of the 5-HT1A receptor, in the prefrontal cortex of subjects with major depression." dans: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 13, Issue 8, pp. 1089-101, (2010) (PubMed).

    Szewczyk, Albert, Burns, Czesak, Overholser, Jurjus, Meltzer, Konick, Dieter, Herbst, May, Rajkowska, Stockmeier, Austin: "Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder." dans: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 12, Issue 2, pp. 155-68, (2009) (PubMed).

    Cordeaux, Pasupathy, Bacon, Charnock-Jones, Smith: "Characterization of serotonin receptors in pregnant human myometrium." dans: The Journal of pharmacology and experimental therapeutics, Vol. 328, Issue 3, pp. 682-91, (2009) (PubMed).

    Iyo, Kieran, Chandran, Albert, Wicks, Bissette, Austin: "Differential regulation of the serotonin 1 A transcriptional modulators five prime repressor element under dual repression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress." dans: Neuroscience, Vol. 163, Issue 4, pp. 1119-27, (2009) (PubMed).

  • Antigène
    Serotonin Receptor 1A (HTR1A)
    Autre désignation
    HTR1A (HTR1A Produits)
    Synonymes
    anticorps 5-HT-dro2A, anticorps 5-HT1ADro, anticorps 5-HT[1A]Dro, anticorps 5-HT[[1ADro]], anticorps 5-HT[[1A]], anticorps 5-HT[[1A]]DRO, anticorps 5HT-R2A, anticorps 5HT-dro2A, anticorps 5HT-drp[[2A]], anticorps 5HT1A, anticorps 5HT[[1ADro]], anticorps 5htdro2a, anticorps CG16720, anticorps DRO2A, anticorps Dm5HTdro2A, anticorps Dmel\\CG16720, anticorps d5-HT1A, anticorps 5htr1a, anticorps htr1a, anticorps HTR1A, anticorps Htr1a, anticorps 5-Ht1a, anticorps Gpcr18, anticorps 5-HT-1A, anticorps 5-HT1A, anticorps 5HT1a, anticorps ADRB2RL1, anticorps ADRBRL1, anticorps G-21, anticorps PFMCD, anticorps RAT5HT1A, anticorps 5ht1a, anticorps adrb2rl1, anticorps adrbrl1, anticorps htr1a-A, anticorps 5-hydroxytryptamine (serotonin) receptor 1A, anticorps 5-hydroxytryptamine receptor 1A, anticorps 5-hydroxytryptamine (serotonin) receptor 1A a, anticorps 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog, anticorps 5-HT1A, anticorps HTR1A, anticorps htr1aa, anticorps Htr1a, anticorps htr1a.L
    Sujet
    This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibits adenylate cyclase activity.
    Alias Symbols: 5HT1a, 5-HT1A, ADRBRL1, ADRB2RL1
    Protein Interaction Partner: UBC, RHOA, GABBR2, GPR26, S1PR1, S1PR3, HTR1D, HTR1B, GNAI3, HTR1A,
    Protein Size: 422
    Poids moléculaire
    46 kDa
    ID gène
    3350
    NCBI Accession
    NM_000524, NP_000515
    UniProt
    P08908
    Pathways
    Signalistation JAK/STAT, Synaptic Membrane, Feeding Behaviour
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