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BLMH anticorps (AA 212-242)

BLMH Reactivité: Humain, Rat, Souris WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1881113
  • Antigène Voir toutes BLMH Anticorps
    BLMH (Bleomycin Hydrolase (BLMH))
    Épitope
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 212-242
    Reactivité
    • 28
    • 28
    • 21
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 41
    • 11
    • 1
    Lapin
    Clonalité
    • 45
    • 8
    Polyclonal
    Conjugué
    • 24
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BLMH est non-conjugé
    Application
    • 46
    • 13
    • 13
    • 13
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Rb
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This BLMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the Central region of human BLMH.
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Ferrando, Velasco, Campo, Lopez-Otin: "Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance." dans: Cancer research, Vol. 56, Issue 8, pp. 1746-50, (1996) (PubMed).

    Brömme, Rossi, Smeekens, Anderson, Payan: "Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization." dans: Biochemistry, Vol. 35, Issue 21, pp. 6706-14, (1996) (PubMed).

  • Antigène
    BLMH (Bleomycin Hydrolase (BLMH))
    Autre désignation
    BLMH (BLMH Produits)
    Synonymes
    anticorps AI035728, anticorps Bh, anticorps Bmh, anticorps wu:fb13c01, anticorps zgc:66261, anticorps bh, anticorps bmh, anticorps BH, anticorps BMH, anticorps bleomycin hydrolase, anticorps Bleomycin hydrolase, anticorps bleomycin hydrolase S homeolog, anticorps BLMH, anticorps pepC, anticorps LOC5569945, anticorps Apre_0140, anticorps Apar_0899, anticorps Smon_1289, anticorps Kfla_1242, anticorps Snas_3912, anticorps BLJ_1941, anticorps Olsu_1085, anticorps PGTDC60_0106, anticorps Blmh, anticorps blmh, anticorps blmh.S
    Sujet
    The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity).
    Poids moléculaire
    52562
    NCBI Accession
    NP_000377
    UniProt
    Q13867
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