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Cyclin B1 anticorps (pSer35)

CCNB1 Reactivité: Humain WB, DB Hôte: Lapin Polyclonal RB42141 unconjugated
N° du produit ABIN1881155
  • Antigène Voir toutes Cyclin B1 (CCNB1) Anticorps
    Cyclin B1 (CCNB1)
    Épitope
    • 23
    • 23
    • 23
    • 16
    • 9
    • 7
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer35
    Reactivité
    • 201
    • 95
    • 62
    • 20
    • 16
    • 16
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 161
    • 47
    • 1
    Lapin
    Clonalité
    • 155
    • 54
    Polyclonal
    Conjugué
    • 110
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Cyclin B1 est non-conjugé
    Application
    • 139
    • 75
    • 57
    • 48
    • 41
    • 40
    • 39
    • 31
    • 30
    • 11
    • 11
    • 11
    • 10
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Dot Blot (DB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This CCNB1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S35 of human CCNB1.
    Clone
    RB42141
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CCNB1 Anticorps primaire
  • Indications d'application
    WB: 1:1100. DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Kreis, Sanhaji, Krämer, Sommer, Rödel, Strebhardt, Yuan: "Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells." dans: Oncogene, Vol. 29, Issue 41, pp. 5591-603, (2010) (PubMed).

    van Zon, Ogink, ter Riet, Medema, te Riele, Wolthuis: "The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit." dans: The Journal of cell biology, Vol. 190, Issue 4, pp. 587-602, (2010) (PubMed).

    Harley, Allan, Sanderson, Clarke: "Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest." dans: The EMBO journal, Vol. 29, Issue 14, pp. 2407-20, (2010) (PubMed).

  • Antigène
    Cyclin B1 (CCNB1)
    Autre désignation
    CCNB1 (CCNB1 Produits)
    Synonymes
    anticorps ccnb, anticorps cycb, anticorps cb267, anticorps cycb1, anticorps wu:fa19g04, anticorps wu:fb16d01, anticorps wu:fb16e07, anticorps wu:fi21c01, anticorps ccnb1, anticorps MGC53596, anticorps CCNB, anticorps Ccnb1-rs1, anticorps Ccnb1-rs13, anticorps CycB1, anticorps Cycb-4, anticorps Cycb-5, anticorps Cycb1-rs1, anticorps cyclin B1, anticorps cyclin B1 S homeolog, anticorps ccnb1, anticorps ccnb1.2, anticorps ccnb1.S, anticorps CCNB1, anticorps Ccnb1, anticorps ccnb1.2.S
    Sujet
    The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq].
    Poids moléculaire
    48337
    NCBI Accession
    NP_114172
    UniProt
    P14635
    Pathways
    Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
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