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MTA1 anticorps (C-Term)

MTA1 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal RB40949 unconjugated
N° du produit ABIN1881556
  • Antigène Voir toutes MTA1 Anticorps
    MTA1 (Metastasis Associated 1 (MTA1))
    Épitope
    • 14
    • 10
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 659-687, C-Term
    Reactivité
    • 55
    • 25
    • 21
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 48
    • 7
    • 1
    Lapin
    Clonalité
    • 49
    • 7
    Polyclonal
    Conjugué
    • 38
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MTA1 est non-conjugé
    Application
    • 45
    • 28
    • 14
    • 11
    • 9
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This MTA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-687 amino acids from the C-terminal region of human MTA1.
    Clone
    RB40949
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Zhu, Guo, Li, Ding, Chen: "Metastasis-associated protein 1 nuclear expression is associated with tumor progression and clinical outcome in patients with non-small cell lung cancer." dans: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 5, Issue 8, pp. 1159-66, (2010) (PubMed).

    Van Rechem, Boulay, Pinte, Stankovic-Valentin, Guérardel, Leprince: "Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells." dans: Molecular and cellular biology, Vol. 30, Issue 16, pp. 4045-59, (2010) (PubMed).

    Yang, Liu, Li: "[Expression of Mta-1 and VEGF and their correlation in the endometrial cancer]." dans: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, Vol. 26, Issue 7, pp. 682-4, (2010) (PubMed).

    Li, Ohshiro, Khan, Kumar: "Requirement of MTA1 in ATR-mediated DNA damage checkpoint function." dans: The Journal of biological chemistry, Vol. 285, Issue 26, pp. 19802-12, (2010) (PubMed).

    Li, Pakala, Reddy, Ohshiro, Peng, Lian, Fu, Kumar: "Revelation of p53-independent function of MTA1 in DNA damage response via modulation of the p21 WAF1-proliferating cell nuclear antigen pathway." dans: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 10044-52, (2010) (PubMed).

  • Antigène
    MTA1 (Metastasis Associated 1 (MTA1))
    Autre désignation
    MTA1 (MTA1 Produits)
    Synonymes
    anticorps Tex22, anticorps metastasis associated 1, anticorps metastasis associated 1 L homeolog, anticorps MTA1, anticorps Mta1, anticorps mta1.L
    Sujet
    This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. [provided by RefSeq].
    Poids moléculaire
    80786
    NCBI Accession
    NP_001190187, NP_004680
    UniProt
    Q13330
    Pathways
    Chromatin Binding
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