BAIAP2
Reactivité: Humain, Souris, Rat
ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Miyahara, Okamura-Oho, Miyashita, Hoshika, Yamada: "Genomic structure and alternative splicing of the insulin receptor tyrosine kinase substrate of 53-kDa protein." dans: Journal of human genetics, Vol. 48, Issue 8, pp. 410-4, (2003) (PubMed).
Oda, Shiratsuchi, Nishimori, Inazawa, Yoshikawa, Taketani, Nakamura, Tokino: "Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1." dans: Cytogenetics and cell genetics, Vol. 84, Issue 1-2, pp. 75-82, (1999) (PubMed).
Okamura-Oho, Miyashita, Ohmi, Yamada: "Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate." dans: Human molecular genetics, Vol. 8, Issue 6, pp. 947-57, (1999) (PubMed).
Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.