MEX3D anticorps (Center)

N° du produit ABIN1887549

Détail du produit anti-MEX3D anticorps

Antigène: MEX3D (Mex-3 Homolog D (MEX3D))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEX3D est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide from near the center of human Rkhd1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur MEX3D

Antigène: MEX3D (Mex-3 Homolog D (MEX3D))

Autre désignation: Rkhd1 (MEX3D Produits)

Synonymes: anticorps RKHD1, anticorps MEX3D, anticorps rkhd1, anticorps mex3, anticorps tino, anticorps rnf193, anticorps ok/sw-cl.4, anticorps MEX-3D, anticorps MEX3, anticorps OK/SW-cl.4, anticorps RNF193, anticorps TINO, anticorps BC059858, anticorps Rkhd1, anticorps mex-3 RNA binding family member D, anticorps mex-3 RNA binding family member D L homeolog, anticorps mex3 RNA binding family member D, anticorps MEX3D, anticorps mex3d.L, anticorps mex3d, anticorps Mex3d

Sujet: Rkhd1, also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module.MEX3 proteins, including Rkhd1, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway.These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms.Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression.Rkhd3 and Rkhd4, but not Rkhd1, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Synonyms: RING finger and KH domain-containing protein 1, MEX3D, TINO, RING finger protein 193, RNF193

UniProt: Q86XN8