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PRDM1 anticorps (C-Term)

PRDM1 Reactivité: Humain Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2017609
  • Antigène Voir toutes PRDM1 Anticorps
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    Épitope
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 63
    • 19
    • 12
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 41
    • 23
    • 3
    • 1
    Lapin
    Clonalité
    • 46
    • 22
    Polyclonal
    Conjugué
    • 46
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PRDM1 est non-conjugé
    Application
    Veuillez nous consulter SVP
    Specificité
    Blimp-1 Antibody, pAb, Rabbit detects endogenous levels of human Blimp-1.
    Réactivité croisée (Details)
    It is predicted to react with mouse Blimp-1 according to sequence homology.
    Reactivity to other species is not tested yet.
    Attributs du produit
    Blimp-1 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Blimp-1 (Swiss Prot: O75626).
    Purification
    Immunoaffinity chromatography
    Immunogène
    KLH-coupled synthetic peptide from C-terminal of human Blimp-1
    Isotype
    IgG
    Top Product
    Discover our top product PRDM1 Anticorps primaire
  • Commentaires

    Positive Control: K562, Ramos

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
    Concentration
    0.5 mg/mL
    Buffer
    Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
  • Chou, Pinto, Curtis, Persaud, Cella, Lin, Edelson, Allen, Colonna, Pearce, Diamond, Egawa: "c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells." dans: Nature immunology, Vol. 15, Issue 9, pp. 884-93, (2014) (PubMed).

    Oestreich, Mohn, Weinmann: "Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile." dans: Nature immunology, Vol. 13, Issue 4, pp. 405-11, (2012) (PubMed).

  • Antigène
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    Autre désignation
    Blimp-1 (PRDM1 Produits)
    Synonymes
    anticorps GB11750, anticorps CG5249, anticorps Dmel\\CG5249, anticorps blimp-1, anticorps dBlimp-1, anticorps dBlimp1, anticorps Blimp-1, anticorps Blimp1, anticorps nrd, anticorps prdm1, anticorps ubo, anticorps wu:fb99c12, anticorps zgc:91885, anticorps MGC52536, anticorps PRDM1, anticorps blimp1, anticorps xblimp1, anticorps prdi-bf1, anticorps BLIMP1, anticorps PRDI-BF1, anticorps ZNFPR1A1, anticorps PR/SET domain 1, anticorps probable serine/threonine-protein kinase DDB_G0282963, anticorps CG5249 gene product from transcript CG5249-RF, anticorps blimp-1, anticorps PR domain containing 1a, with ZNF domain, anticorps PR domain 1 S homeolog, anticorps B lymphocyte induced maturation protein 1, anticorps PR domain 1, anticorps PR domain containing 1, with ZNF domain, anticorps PRDM1, anticorps LOC408295, anticorps Blimp-1, anticorps CpipJ_CPIJ007425, anticorps prdm1a, anticorps prdm1.S, anticorps prdm1, anticorps Prdm1
    Sujet
    Blimp-1 (B lymphocyte-induced maturation protein) is a nuclear zinc-finger containing transcriptional repressor and plays an important role in terminal B-cell development. Expression of Blimp-1 is sufficient to drive terminal differentiation of BCL1 lymphoma cells into antibody secreting plasma cells, increasing the expression of the cell surface marker Syndecan-1. In addition, Blimp-1 has been found during macrophage differentiation and in a subset of T-cells, which suggests that it may play a wider role in homeostasis and differentiation.
    UniProt
    O75626
    Pathways
    Regulation of Muscle Cell Differentiation
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