PRDM1 anticorps (C-Term)
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- Antigène Voir toutes PRDM1 Anticorps
- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PRDM1 est non-conjugé
- Application
- Veuillez nous consulter SVP
- Specificité
- Blimp-1 Antibody, pAb, Rabbit detects endogenous levels of human Blimp-1.
- Réactivité croisée (Details)
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It is predicted to react with mouse Blimp-1 according to sequence homology.
Reactivity to other species is not tested yet. - Attributs du produit
- Blimp-1 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Blimp-1 (Swiss Prot: O75626).
- Purification
- Immunoaffinity chromatography
- Immunogène
- KLH-coupled synthetic peptide from C-terminal of human Blimp-1
- Isotype
- IgG
- Top Product
- Discover our top product PRDM1 Anticorps primaire
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- Commentaires
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Positive Control: K562, Ramos
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
- Concentration
- 0.5 mg/mL
- Buffer
- Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
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c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells." dans: Nature immunology, Vol. 15, Issue 9, pp. 884-93, (2014) (PubMed).
: "Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile." dans: Nature immunology, Vol. 13, Issue 4, pp. 405-11, (2012) (PubMed).
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c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells." dans: Nature immunology, Vol. 15, Issue 9, pp. 884-93, (2014) (PubMed).
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- Antigène
- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
- Autre désignation
- Blimp-1 (PRDM1 Produits)
- Synonymes
- anticorps GB11750, anticorps CG5249, anticorps Dmel\\CG5249, anticorps blimp-1, anticorps dBlimp-1, anticorps dBlimp1, anticorps Blimp-1, anticorps Blimp1, anticorps nrd, anticorps prdm1, anticorps ubo, anticorps wu:fb99c12, anticorps zgc:91885, anticorps MGC52536, anticorps PRDM1, anticorps blimp1, anticorps xblimp1, anticorps prdi-bf1, anticorps BLIMP1, anticorps PRDI-BF1, anticorps ZNFPR1A1, anticorps PR/SET domain 1, anticorps probable serine/threonine-protein kinase DDB_G0282963, anticorps CG5249 gene product from transcript CG5249-RF, anticorps blimp-1, anticorps PR domain containing 1a, with ZNF domain, anticorps PR domain 1 S homeolog, anticorps B lymphocyte induced maturation protein 1, anticorps PR domain 1, anticorps PR domain containing 1, with ZNF domain, anticorps PRDM1, anticorps LOC408295, anticorps Blimp-1, anticorps CpipJ_CPIJ007425, anticorps prdm1a, anticorps prdm1.S, anticorps prdm1, anticorps Prdm1
- Sujet
- Blimp-1 (B lymphocyte-induced maturation protein) is a nuclear zinc-finger containing transcriptional repressor and plays an important role in terminal B-cell development. Expression of Blimp-1 is sufficient to drive terminal differentiation of BCL1 lymphoma cells into antibody secreting plasma cells, increasing the expression of the cell surface marker Syndecan-1. In addition, Blimp-1 has been found during macrophage differentiation and in a subset of T-cells, which suggests that it may play a wider role in homeostasis and differentiation.
- UniProt
- O75626
- Pathways
- Regulation of Muscle Cell Differentiation
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