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SERPINB9 anticorps

SERPINB9 Reactivité: Souris WB, FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2192172
  • Antigène Voir toutes SERPINB9 Anticorps
    SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
    Reactivité
    • 37
    • 9
    • 8
    • 1
    • 1
    Souris
    Hôte
    • 31
    • 7
    • 1
    Lapin
    Clonalité
    • 33
    • 6
    Polyclonal
    Conjugué
    • 27
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SERPINB9 est non-conjugé
    Application
    • 29
    • 16
    • 11
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Stérilité
    0.2 μm filtered
    Top Product
    Discover our top product SERPINB9 Anticorps primaire
  • Indications d'application
    For flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    Restrictions
    For Research Use only
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Date de péremption
    12 months
  • Zhang, Byrne, Liu, Wang, Oxenius, Ashton-Rickardt: "Differential survival of cytotoxic T cells and memory cell precursors." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 6, pp. 3483-91, (2007) (PubMed).

    Zhang, Liu, Park, Wang, Byrne, Murmann, Bahr, Peter, Olson, Belaaouaj, Ashton-Rickardt: "Serine protease inhibitor 6-deficient mice have increased neutrophil immunity to Pseudomonas aeruginosa." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 7, pp. 4390-6, (2007) (PubMed).

  • Antigène
    SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
    Autre désignation
    Spi-6 (SERPINB9 Produits)
    Synonymes
    anticorps SERPINB9, anticorps BB283241, anticorps CAP-3, anticorps CAP3, anticorps PI-9, anticorps PI9, anticorps Spi6, anticorps ovalbumin, anticorps serpin family B member 9, anticorps serpin peptidase inhibitor, clade B (ovalbumin), member 9, anticorps serine (or cysteine) peptidase inhibitor, clade B, member 9, anticorps Serpinb9, anticorps SERPINB9
    Sujet
    The polyclonal antibody recognizes mouse Spi-6, also known as serpin B9, a cytoplasmic serine protease inhibitor of ~42 kD. Spi-6 is expressed in dendritic cells, lymphocytes and specific cell types at immune- privileged sites. It inactivates granzyme B, a natural occurring inducer of programmed cell death. As such, Spi-6 functions as anti-apoptotic protein. In cytotxic T cells (CTL), Spi-6 is required to protect clonal bursts (expansion) from granzyme B induced cell death. However, it is not required for the development of memory cells. Expression of SPI-6 is of crucial importance in the escape of several tumors from a CTL response and is, therefore, a parameter that influences the feasibility of CTL-mediated immunotherapy of cancer. The polyclonal antibody shows no crossreactivity with mouse proteins related to Spi-6. Aliases Cytoplasmic antiproteinase 3, serpin B9, PI-9 Immunogen Recombinant GST-Spi-6
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