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SNCA anticorps

SNCA Reactivité: Humain WB, ELISA, IHC (p), IHC (f) Hôte: Souris Monoclonal 4D6 unconjugated
N° du produit ABIN236423
  • Antigène Voir toutes SNCA Anticorps
    SNCA (Synuclein, alpha (SNCA))
    Reactivité
    • 308
    • 209
    • 209
    • 14
    • 10
    • 10
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 247
    • 103
    • 6
    • 1
    • 1
    • 1
    Souris
    Clonalité
    • 231
    • 129
    Monoclonal
    Conjugué
    • 159
    • 25
    • 22
    • 17
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    Cet anticorp SNCA est non-conjugé
    Application
    • 251
    • 170
    • 113
    • 84
    • 80
    • 74
    • 68
    • 54
    • 49
    • 48
    • 23
    • 21
    • 13
    • 9
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    Reacts well with alpha-synuclein in Western blots and frozen and formalin-fixed/paraffin-embedded tissue sections. Recognizes human alpha-synuclein. Synuclein-alpha is the major component of Lewy bodies and Lewy neuritis in sporadic PD. dementia with Lewy Bodies and Lewy Body variant of AD. Lewy bodies are composed of truncated and phosphorylated intermediate neurofilament proteins, alpha synuclein, ubiquitin and associated enzymes. The synuclein phosphoproteins (15-20 kDa) are small highly conserved proteins in vertebrates. The synuclein family includes alpha and beta synucleins and loosely related gamma-synuclein and synoretin. The expression is abundant in neurons and typically localized at presynaptic terminals.
    Attributs du produit
    MAb to Synuclein Alpha, Monoclonal antibody to Human Synuclein alpha, Tissue culture supernatant
    Purification
    Protein A column Chromatography. Cell culture
    Immunogène
    Purified E. coli produced human alpha-synuclein
    Clone
    4D6
    Isotype
    IgG1
    Top Product
    Discover our top product SNCA Anticorps primaire
  • Indications d'application
    Western/Dot blot (1:100 - 1:10.000) ELISA Immunohistochemistry: (1:100 - 1:1.000) frozen and formalin-fixed paraffin-embedded tissues (No formic acid, enzyme or HIER required). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS.
    Agent conservateur
    Without preservative
    Conseil sur la manipulation
    Avoid multiple freeze/thaw cycles.
    Centrifuge product if not completely clear after standing at room temperature.
    Prepare working dilution only prior to immediate use.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C.
  • Antigène
    SNCA (Synuclein, alpha (SNCA))
    Autre désignation
    Synuclein alpha (SNCA Produits)
    Synonymes
    anticorps snca, anticorps MGC64356, anticorps LOC619283, anticorps NACP, anticorps alphaSYN, anticorps PARK1, anticorps PARK4, anticorps PD1, anticorps synuclein alpha L homeolog, anticorps alpha-synuclein, anticorps synuclein alpha, anticorps synuclein, alpha, anticorps snca.L, anticorps LOC619283, anticorps SNCA, anticorps Snca
    Pathways
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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