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SOS1 anticorps

SOS1 Reactivité: Humain, Souris WB, IF, EIA Hôte: Souris Monoclonal SOS-1 unconjugated
N° du produit ABIN238504
  • Antigène Voir toutes SOS1 Anticorps
    SOS1 (Son of Sevenless Homolog 1 (SOS1))
    Reactivité
    • 26
    • 11
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 18
    • 10
    • 1
    Souris
    Clonalité
    • 19
    • 10
    Monoclonal
    Conjugué
    • 26
    • 1
    • 1
    • 1
    Cet anticorp SOS1 est non-conjugé
    Application
    • 21
    • 14
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    The antibody SOS-01 reacts with human Sos, an ubiquitously expressed 150 kDa intracellular protein.
    Attributs du produit
    Synonyms: SOS-1, Son of sevenless homolog 1
    Purification
    Protein A affinity chromatography.
    Immunogène
    Peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human Sos protein.
    Clone
    SOS-1
    Isotype
    IgG1
    Top Product
    Discover our top product SOS1 Anticorps primaire
  • Indications d'application
    Western Blotting under reducing conditions (1 μg/mL): Positive control: HeLa human cervix carcinoma cell line. Immunocytochemistry. ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4 with 15 mM sodium azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze/thaw cycles.
    Shelf life: One year from despatch.
    Date de péremption
    12 months
  • Antigène
    SOS1 (Son of Sevenless Homolog 1 (SOS1))
    Autre désignation
    SOS1 (SOS1 Produits)
    Synonymes
    anticorps GF1, anticorps GGF1, anticorps GINGF, anticorps HGF, anticorps NS4, anticorps 4430401P03Rik, anticorps 9630010N06, anticorps AI449023, anticorps SOS Ras/Rac guanine nucleotide exchange factor 1, anticorps son of sevenless homolog 1 (Drosophila), anticorps SOS1, anticorps Sos1
    Classe de substances
    Viral Protein
    Sujet
    The guanine nucleotide exchange factor Sos (Son-of-sevenless) is a complex multidomain protein that activates the small GTPase Ras (H-Ras, K-Ras, N-Ras, but not functionally distinct R-Ras) in response to receptor tyrosine kinase stimulation. Nucleotide exchange activity of Sos is stimulated by allosteric Ras binding. By another (separable) guanine exchange factor domain domain Sos modulates activity of Rac/Rho GTPases. Sos thus integrates signals that affect both gene expression and cytoskeletal reorganization, the Sos-mediated Ras-activation and Rac activation differ in composition and stability of the formed complex.Synonyms: SOS-1, Son of sevenless homolog 1
    ID gène
    6654
    UniProt
    Q07889
    Pathways
    Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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