CRHR1 anticorps (AA 107-117)
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- Antigène Voir toutes CRHR1 Anticorps
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
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Épitope
- AA 107-117
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Reactivité
- Humain, Souris, Rat
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CRHR1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Fonction
- CRHR1 / CRF-R (aa 107 - 117)
- Séquence
- NEEKKSKVHY H
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Classe de qualité
- Verified
- Immunogène
- Peptide with sequence C-NEEKKSKVHYH, from the internal region of the protein sequence according to NP_004373.2.
- Isotype
- IgG
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- Indications d'application
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Western Blot: Approx 60 kDa band observed in Human Brain (Cerebellum), Colon, Rat Brain and Mouse spinal cord lysates (calculated MW of 47.7 kDa according to NP_004373.2). The observed molecular weight corresponds to earlier findings in literature with di
Peptide ELISA: antibody detection limit dilution 1:128000.
- Commentaires
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Immunofluorescence: Expression of the protein seen in the membranes, vesicles and cytoplasm of MCF7 and Neuro2a cells. Recommended concentration: 10μg/ml.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Minimize freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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Exchange protein directly activated by cAMP 2 is required for corticotropin-releasing hormone-mediated spine loss." dans: The European journal of neuroscience, Vol. 50, Issue 7, pp. 3108-3114, (2020) (PubMed).
: "Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor." dans: The Journal of physiology, Vol. 590, Issue Pt 16, pp. 3701-17, (2012) (PubMed).
: "Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 9, pp. G925-36, (2012) (PubMed).
: "
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Exchange protein directly activated by cAMP 2 is required for corticotropin-releasing hormone-mediated spine loss." dans: The European journal of neuroscience, Vol. 50, Issue 7, pp. 3108-3114, (2020) (PubMed).
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- Antigène
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
- Autre désignation
- CRHR1 (CRHR1 Produits)
- Synonymes
- anticorps CRF-R, anticorps CRF-R-1, anticorps CRF-R1, anticorps CRF1, anticorps CRFR-1, anticorps CRFR1, anticorps CRH-R-1, anticorps CRH-R1, anticorps CRH-R1h, anticorps CRHR, anticorps CRHR1L, anticorps CRHR1f, anticorps Crhr, anticorps crhr1, anticorps crhr1-A, anticorps CRHR1, anticorps CRHR1-IT1-CRHR1, anticorps MGC57346-CRHR1, anticorps corticotropin releasing hormone receptor 1, anticorps corticotropin releasing hormone receptor 1, gene 2 S homeolog, anticorps corticotropin-releasing factor receptor 1, anticorps LINC02210-CRHR1 readthrough, anticorps CRHR1, anticorps Crhr1, anticorps crhr1.2.S, anticorps LOC610380, anticorps LOC100065598, anticorps LINC02210-CRHR1, anticorps crhr1
- Sujet
- CRHR1, CRF-R, corticotropin releasing hormone receptor 1, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f, corticotropin releasing hormone receptor variant 1h, seven transmembrane helix receptor
- ID gène
- 1394, 12921, 58959
- NCBI Accession
- NP_004373
- Pathways
- Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity
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