RNF139 anticorps

N° du produit ABIN2458704

Détail du produit anti-RNF139 anticorps

Antigène: RNF139 (Ring Finger Protein 139 (RNF139))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF139 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF139.

Information d'application

Indications d'application: RNF139 antibody can be used for detection of RNF139 by ELISA at 1:312500. RNF139 antibody can be used for detection of RNF139 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RNF139 antibody at -20 °C.

Détails sur RNF139

Antigène: RNF139 (Ring Finger Protein 139 (RNF139))

Autre désignation: RNF139 (RNF139 Produits)

Synonymes: anticorps HRCA1, anticorps RCA1, anticorps TRC8, anticorps 4930555P18Rik, anticorps zgc:175173, anticorps rnf139, anticorps ring finger protein 139, anticorps ring finger protein 139 S homeolog, anticorps RNF139, anticorps Rnf139, anticorps rnf139, anticorps rnf139.S

Sujet: RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

Poids moléculaire: 76 kDa

ID gène: 11236

NCBI Accession: NP_009149

UniProt: Q8WU17