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ITGAL anticorps (Biotin)

ITGAL Reactivité: Humain FACS Hôte: Souris Monoclonal OFYS Biotin
N° du produit ABIN264308
  • Antigène Voir toutes ITGAL Anticorps
    ITGAL (Integrin alpha-L (ITGAL))
    Reactivité
    • 133
    • 76
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 104
    • 61
    • 49
    • 1
    Souris
    Clonalité
    • 160
    • 54
    • 1
    Monoclonal
    Conjugué
    • 74
    • 29
    • 26
    • 21
    • 11
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ITGAL est conjugé à/à la Biotin
    Application
    • 140
    • 54
    • 35
    • 32
    • 32
    • 27
    • 24
    • 24
    • 11
    • 8
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    This antibody reacts with LFA-1 alpha. This antibody blocks cell-cell adhesion and adhesion mediated events such as cell mediated cytotoxicity.
    Attributs du produit
    Synonyms: Integrin alpha-L, LFA1, LFA-1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocytefunction-associated molecule 1 alpha chain, CD11 antigen-like family member A
    Clone
    OFYS
    Isotype
    IgG2a
    Top Product
    Discover our top product ITGAL Anticorps primaire
  • Indications d'application
    Flow Cytometry. Characterization of LFA-1 immunodeficiency. Monitoring of subsets in peripheral blood. Graft-versus-host disease. Analysis of CTL-mediated cytotoxicity. Studies of transplantation rejection. Functional studies of cell adhesion molecules.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Protocole
    PBMC: Add 10 ul of MAB/10e6 PBMC in 100 ul PBS. Mix gently and incubate for 15 minutes at 2-8°C. Wash twice with PBS and analyze or fix with 0. 5% v/v of paraformaldehyde in PBS andanalyze. WHOLE BLOOD: Add 10 ul of MAB/100 ul of whole blood. Mix gently and incubate for 15 minutes at room temperature (20°C). Lyse the whole blood. Wash once with PBS and analyze or fix with 0. 5% v/v of paraformaldehyde in PBS andanalyze. See instrument manufacturers instructions for Lysed Whole Blood andImmunofluorescence analysis with a flow cytometer or microscope.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.2 % protein carrier and 0.08 % Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C. Do Not Freeze!
    Shelf life: One year from despatch.
    Date de péremption
    12 months
  • Antigène
    ITGAL (Integrin alpha-L (ITGAL))
    Autre désignation
    CD11a / ITGAL (ITGAL Produits)
    Synonymes
    anticorps CD11A, anticorps LFA-1, anticorps LFA1A, anticorps (p180), anticorps Cd11a, anticorps LFA-1A, anticorps Ly-15, anticorps Ly-21, anticorps CD11a, anticorps ITGAL, anticorps integrin subunit alpha L, anticorps integrin alpha L, anticorps ITGAL, anticorps Itgal
    Sujet
    CD11a, Leukocyte Function Antigen-1 (LFA-1) complex is a heterodimeric glycoprotein consisting of two non-covalently linked chains, a 180 kDa alpha chain and a 95 kDa beta chain. It is a member of the integrin supergene family of adhesion molecules, and is on virtually all peripheral blood leukocytes. The molecule binds to ICAM-1, 2 and 3 and mediates cell-cell adhesion.Synonyms: CD11 antigen-like family member A, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain
    ID gène
    3683
    UniProt
    P20701
    Pathways
    Activated T Cell Proliferation, Integrin Complex
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