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Acetylated Lysine anticorps (acetylated) (HRP)

WB, IP, IF, EIA Hôte: Lapin Polyclonal HRP
N° du produit ABIN264879
  • Antigène Tous les produits Acetylated Lysine
    Acetylated Lysine
    Épitope
    • 11
    • 1
    • 1
    acetylated
    Reactivité
    Veuillez nous consulter SVP
    Hôte
    • 28
    • 24
    Lapin
    Clonalité
    • 26
    • 25
    Polyclonal
    Conjugué
    • 23
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Acetylated Lysine est conjugé à/à la HRP
    Application
    • 49
    • 39
    • 34
    • 22
    • 12
    • 12
    • 11
    • 11
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Purification
    Affinity Chromatography
    Immunogène
    Acetylated KLH
    Isotype
    IgG
  • Indications d'application
    Western blot (6). Immunoprecipitation (7). ELISA. Immonoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % Sodium Azide, 50 % Glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Acetylated Lysine
    Abstract
    Acetylated Lysine Produits
    Synonymes
    anticorps C-K-RAS, anticorps CFC2, anticorps K-RAS2A, anticorps K-RAS2B, anticorps K-RAS4A, anticorps K-RAS4B, anticorps KI-RAS, anticorps KRAS1, anticorps KRAS2, anticorps NS, anticorps NS3, anticorps RASK2, anticorps KRAS proto-oncogene, GTPase, anticorps KRAS
    Classe de substances
    Chemical
    Sujet
    Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common posttranscriptional modification of Lysine involves acetylation (1). The conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) (2). Protein posttranslational reversible lysine N?-acetylation and deacetylation have been recognized as an emerging intracellular signaling mechanism that plays critical roles in regulating gene transcription, cell-cycle progression, apoptosis, DNA repair, and cytoskeletal organization (3). The regulation of protein acetylation status is impaired in the pathologies of cancer and polyglutamine diseases (4), and HDACs have become promising targets for anticancer drugs currently in development (5).Synonyms: AcK, acetyl Lysine, acetyl-Lysine
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