MAGI3 anticorps

N° du produit ABIN264919

Détail du produit anti-MAGI3 anticorps

Antigène: MAGI3 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 3 (MAGI3))

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGI3 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to MAGI-3, GKWW.

Purification: Purified

Immunogène: Recombinant protein corresponding to the guanylate kinase-WW domain of MAGI-3.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1 - 10 μg/mL. Detects a 130 kDa band in cells transfected with full-lengthMAGI-3 protein.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur MAGI3

Antigène: MAGI3 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 3 (MAGI3))

Autre désignation: MAGI3 (MAGI3 Produits)

Synonymes: anticorps Slipr, anticorps MAGI-3, anticorps RP4-730K3.1, anticorps dJ730K3.2, anticorps 4732496O19Rik, anticorps 6530407C02Rik, anticorps AA407180, anticorps AI120132, anticorps mKIAA1634, anticorps membrane associated guanylate kinase, WW and PDZ domain containing 3, anticorps Magi3, anticorps MAGI3

Sujet: Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a novel, 130 kDa guanylate kinase which is part of a family of multi-PDZ domain containing guanylate kinases. These guanylate kinases are localized to epithelial cell tight junctions. MAGI3 and PTEN/MMAC cooperate to modulate the kinase activity of AKT/protein kinase B (PKB). MAGI3 positions the PTEN/MMAC phosphatase to specific subcellular locations that are involved with the regulation of cell proliferation and survival. MAGI3, as well as other proteins in this family, are made up of an N-terminal guanylate kinase domain, followed by a WW domain, named for two conserved tryptophan residues and first identified as two repeats in mouse YAP65, which is them followed by 5 PDZ domains.Synonyms: MAGI-3, Membrane-associated guanylate kinase, Membrane-associated guanylate kinase inverted 3, WW and PDZ domain-containing protein 3

ID gène: 260425

NCBI Accession: NP_001136254

UniProt: Q5TCQ9