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BCL10 anticorps (AA 5-19)

BCL10 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN264992
  • Antigène Voir toutes BCL10 Anticorps
    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
    Épitope
    • 17
    • 15
    • 10
    • 9
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 5-19
    Reactivité
    • 104
    • 37
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 75
    • 29
    Lapin
    Clonalité
    • 62
    • 43
    Polyclonal
    Conjugué
    • 48
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BCL10 est non-conjugé
    Application
    • 79
    • 34
    • 32
    • 32
    • 29
    • 20
    • 13
    • 13
    • 13
    • 11
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    This antibody reacts to BCL10.
    Purification
    Purified
    Immunogène
    Synthetic peptide corresponding to amino acids 5 to 19 of the human BCL-10 protein.
    Isotype
    IgG
    Top Product
    Discover our top product BCL10 Anticorps primaire
  • Indications d'application
    Western Blot: 1 μg/mL. Detects a 31 kDa band in Raji whole cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline solution containing 0.02 % sodium azide as a preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    DO NOT FREEZE!
    Stock
    4 °C
    Stockage commentaire
    The antibody can be shipped at ambient temperature. Store (in aliquots) at 2-8 °C.
  • Antigène
    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
    Autre désignation
    Bcl-10 (BCL10 Produits)
    Synonymes
    anticorps CARMEN, anticorps CIPER, anticorps CLAP, anticorps c-E10, anticorps mE10, anticorps BCL10, anticorps AI132454, anticorps BCL-10, anticorps C81403, anticorps ME10, anticorps cE10, anticorps bcl10, anticorps B-cell CLL/lymphoma 10, anticorps B-cell lymphoma/leukemia 10-like, anticorps B cell leukemia/lymphoma 10, anticorps B-cell lymphoma/leukemia 10, anticorps BCL10, anticorps Bcl10, anticorps bcl10, anticorps LOC100223183
    Sujet
    Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP (1-6). Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene. Overexpression of Bcl10 induces JNK, p38, and NF-kB activation (1,2,4,6). Bcl10 interacts with caspase-9 and enhances pro-caspase-9 processing (3) and induces apoptosis through caspase-9 activation (3.6). BCL10 exhibits a variety of mutations in MALT lymphomas and in B and T cell lineage lymphomas indicating that it may be commonly involved in the pathogenesis of human malignancy (1,5). BCL10 is expressed in many human and murine tissues and cell lines (2-6).Synonyms: B-cell CLL/lymphoma 10, BCL10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, CLAP, Cellular homolog of vCARMEN, Cellular-E10, Mammalian CARD-containing adapter molecule E10, c-E10, cCARMEN, hCLAP, mE10
    ID gène
    8915
    NCBI Accession
    NP_003912
    UniProt
    O95999
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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