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LY96 anticorps (Middle Region)

LY96 Reactivité: Humain, Souris, Rat WB, IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN265133
  • Antigène Voir toutes LY96 Anticorps
    LY96 (Lymphocyte Antigen 96 (LY96))
    Épitope
    • 8
    • 8
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 56
    • 12
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 41
    • 19
    Lapin
    Clonalité
    • 44
    • 16
    Polyclonal
    Conjugué
    • 29
    • 10
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LY96 est non-conjugé
    Application
    • 42
    • 22
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Purified
    Immunogène
    Rabbit polyclonal MD-2 antibody was raised against a peptide corresponding to amino acids near the middle region of human MD-2.
    Isotype
    IgG
    Top Product
    Discover our top product LY96 Anticorps primaire
  • Indications d'application
    Western Blot: 0,5 - 1 μg/mL. Immunohistochemistry. Found in the liver and spleen, the secreted protein Lymphocyte antigen 96/MD-2ooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS),and with TLR2 in the response to cell wall components from Gram-positive andGram-negative bacteria.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline with 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • Antigène
    LY96 (Lymphocyte Antigen 96 (LY96))
    Autre désignation
    MD-2 (LY96 Produits)
    Synonymes
    anticorps MD2, anticorps ESOP-1, anticorps MD-2, anticorps ly-96, anticorps Ly-96, anticorps Md2, anticorps lymphocyte antigen 96, anticorps LY96, anticorps Ly96
    Sujet
    MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1 - 3). TLRs are signaling molecules that recognize different pathogenassociated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS (5,6). The specificity of this response is determined by the species of MD-2, e.g., human MD-2 can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4 (7).Synonyms: ESOP-1, ESOP1, LY96, Lymphocyte antigen 96, MD2
    ID gène
    9606
    UniProt
    Q9Y6Y9
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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