Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Bcl-2 anticorps (AA 41-54) (Alexa Fluor 488)

BCL2 Reactivité: Humain FACS Hôte: Souris Monoclonal 1E2 Alexa Fluor 488
N° du produit ABIN2657052
  • Antigène Voir toutes Bcl-2 (BCL2) Anticorps
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Épitope
    • 53
    • 37
    • 23
    • 22
    • 21
    • 18
    • 17
    • 16
    • 16
    • 16
    • 15
    • 14
    • 13
    • 10
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-54
    Reactivité
    • 453
    • 190
    • 186
    • 38
    • 34
    • 22
    • 22
    • 19
    • 17
    • 16
    • 12
    • 5
    • 5
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 357
    • 123
    • 6
    • 2
    • 1
    • 1
    • 1
    Souris
    Clonalité
    • 354
    • 136
    Monoclonal
    Conjugué
    • 217
    • 35
    • 34
    • 25
    • 25
    • 15
    • 14
    • 12
    • 11
    • 11
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Bcl-2 est conjugé à/à la Alexa Fluor 488
    Application
    • 397
    • 200
    • 168
    • 123
    • 107
    • 103
    • 92
    • 74
    • 64
    • 33
    • 29
    • 25
    • 18
    • 8
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
    Immunogène
    AA 41-54 of human bcl-2 oncoprotein
    Clone
    1E2
    Isotype
    IgG1
    Top Product
    Discover our top product BCL2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect from prolonged exposure to light. Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C
  • Antigène
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Autre désignation
    Bcl-2 (BCL2 Produits)
    Synonymes
    anticorps Bcl-2, anticorps PPP1R50, anticorps bcl-2, anticorps AW986256, anticorps C430015F12Rik, anticorps D630044D05Rik, anticorps D830018M01Rik, anticorps BCL-2, anticorps Bcl2, anticorps BCL2, apoptosis regulator, anticorps B cell leukemia/lymphoma 2, anticorps B-cell CLL/lymphoma 2a, anticorps B-cell CLL/lymphoma 2 protein, anticorps BCL2, anticorps Bcl2, anticorps bcl2a, anticorps BCL-2
    Sujet
    Bcl-2 is a conserved anti-apoptotic protein that plays important roles in normal immunity. It forms homodimers or heterodimers with other Bcl-2 family members. This protein regulates apoptosis through controlling mitochondrial fusion and fission. Phosphorylation of Bcl-2 has been shown to enhance activity to allow response to extracellular growth-factor-mediated signals. Bcl-2 is also regulated by IRES, miR-15a, miR-16-1 and RNA-BP nucleolin. Chromosome 18q21.3 translocation and overexpression of Bcl-2 is frequently observed in follicular lymphomas and some diffuse large B-cell lymphomas.
    Pathways
    Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Vous êtes ici:
Support technique