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Keratin 7/17 anticorps

KRT7/17 Reactivité: Humain, Boeuf (Vache), Porc FACS Hôte: Souris Monoclonal C-46 unconjugated
N° du produit ABIN2664920
  • Antigène Voir toutes Keratin 7/17 (KRT7/17) Anticorps
    Keratin 7/17 (KRT7/17)
    Reactivité
    Humain, Boeuf (Vache), Porc
    Hôte
    • 4
    Souris
    Clonalité
    • 4
    Monoclonal
    Conjugué
    • 4
    Cet anticorp Keratin 7/17 est non-conjugé
    Application
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aucune reactivité croisée
    Souris, Rat (Rattus), Lapin
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    C-46
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product KRT7/17 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    Keratin 7/17 (KRT7/17)
    Autre désignation
    Cytokeratin 7/17 (KRT7/17 Produits)
    Synonymes
    anticorps KRT7, anticorps CK7, anticorps keratin 7, anticorps KRT7
    Sujet
    Cytokeratins are proteins that are involved in the cytoskeleton. The cytokeratin proteins are heterotetramers composed of two type I and two type II subunits. Cytokeratin 17 is a type I protein and cytokeratin 7 is a type II intermediate filament protein, each protein contains three coiled-coil domains. Cytokeratin 7 has an approximate molecular weight of 54 kD, cytokeratin 17 has an approximate molecular weight of 46 kD. Cytokeratin 17 is expressed in the basal cells of complex epithelia, but not in stratified or simple epithelia. Cytokeratin 7 is expressed in the epidermis, bronchus, and mesothelium but not in the colon, exocervix or liver. Mutations in cytokeratin 17 have been shown to result in pachyonychia congenital. Cytokeratin 17 has been shown to interact with the EGF receptor. Cytokeratin 7 has been shown to interact with the EGF receptor and heat shock protein 70 kD1A. The C-46 monoclonal antibody recognizes human, bovine and porcine (but not mouse, rat, or rabbit) cytokeratin 7 and cytokeratin 17 and is useful for Western blotting.This antibody has also been reported to be useful for immunoprecipitation, immunohistochemistry (paraffin sections), and immunocytochemistry.
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