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EPO anticorps

EPO Reactivité: Humain FACS Hôte: Souris Monoclonal M0312E3 unconjugated
N° du produit ABIN2664955
  • Antigène Voir toutes EPO Anticorps
    EPO (Erythropoietin (EPO))
    Reactivité
    • 122
    • 31
    • 24
    • 7
    • 6
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 107
    • 48
    • 2
    • 2
    • 1
    Souris
    Clonalité
    • 109
    • 51
    Monoclonal
    Conjugué
    • 89
    • 17
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EPO est non-conjugé
    Application
    • 116
    • 73
    • 48
    • 41
    • 29
    • 14
    • 14
    • 13
    • 13
    • 13
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    M0312E3
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product EPO Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    EPO (Erythropoietin (EPO))
    Autre désignation
    EPO (EPO Produits)
    Synonymes
    anticorps EPO, anticorps EP, anticorps MVCD2, anticorps erythropoietin, anticorps erythropoietin S homeolog, anticorps erythropoietin a, anticorps EPO, anticorps epo, anticorps epo.S, anticorps Epo, anticorps epoa
    Classe de substances
    Hormone
    Sujet
    EPO is the major regulator of differentiation, proliferation, and survival of erythroid progenitors. Hypoxia induces erythropoiesis which causes cells to produce hypoxia inducible factor (HIF) that is directly involved in EPO expression. HIF-Prolyl hydroxylase (HIF-PH) is a sensor of levels of iron, oxygen, and metabolic activity. High levels of HIF protein induce EPO production in the kidneys and liver, and mobilize iron to support erythropoiesis. EPO has been used in the treatment of anemia associated with a number of conditions, such as chronic kidney disease, cancer patients on chemotherapy, and antiviral HIV therapy.
    Pathways
    Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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