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Integrin beta 4 anticorps

ITGB4 Reactivité: Humain FACS Hôte: Rat Monoclonal 439 unconjugated
N° du produit ABIN2688875
  • Antigène Voir toutes Integrin beta 4 (ITGB4) Anticorps
    Integrin beta 4 (ITGB4)
    Reactivité
    • 85
    • 30
    • 26
    • 3
    • 3
    • 1
    Humain
    Hôte
    • 57
    • 39
    • 12
    • 2
    Rat
    Clonalité
    • 59
    • 51
    Monoclonal
    Conjugué
    • 59
    • 9
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Integrin beta 4 est non-conjugé
    Application
    • 56
    • 47
    • 32
    • 30
    • 21
    • 17
    • 15
    • 13
    • 13
    • 9
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Marque
    BD Pharmingen™
    Attributs du produit
    Reacts with CD104, integrin β4 chain, a 205 kDa transmembrane glycoprotein, which associates with CD49f (integrin α6 chain) to form the α6/β4 (CD49f/CD104) complex. It is expressed on epithelial cells, Schwann cells, and some tumor cells. The CD49f/CD104 complex is located in the hemidesmosomes of the epidermis, suggesting its role in epidermal cell-basement membrane adhesion. The clone 439-9B was clustered as CD104 at the fifth Human Leucocyte Differentiation Antigen International Workshop. It may be used for immunoprecipitation, immunoblotting and immunohistochemistry on frozen tissue sections. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of A431, an epidermal carcinoma cell line, analyzed on a FACScan

    BD Pharmingen™ Purified Rat Anti-Human CD104 - Purified - Clone 439-9B - Isotype Rat IgG2b, κ - Reactivity Hu - 0.1 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Clone
    439
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product ITGB4 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C.
  • Jones, Kurpakus, Cooper, Quaranta: "A function for the integrin alpha 6 beta 4 in the hemidesmosome." dans: Cell regulation, Vol. 2, Issue 6, pp. 427-38, (1991) (PubMed).

    Sonnenberg, Calafat, Janssen, Daams, van der Raaij-Helmer, Falcioni, Kennel, Aplin, Baker, Loizidou: "Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion." dans: The Journal of cell biology, Vol. 113, Issue 4, pp. 907-17, (1991) (PubMed).

    Tamura, Rozzo, Starr, Chambers, Reichardt, Cooper, Quaranta: "Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4." dans: The Journal of cell biology, Vol. 111, Issue 4, pp. 1593-604, (1990) (PubMed).

    Hemler, Crouse, Sonnenberg: "Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines." dans: The Journal of biological chemistry, Vol. 264, Issue 11, pp. 6529-35, (1989) (PubMed).

  • Antigène
    Integrin beta 4 (ITGB4)
    Autre désignation
    CD104 (ITGB4 Produits)
    Synonymes
    anticorps AA407042, anticorps C230078O20, anticorps CD104, anticorps integrin subunit beta 4, anticorps integrin beta 4, anticorps ITGB4, anticorps Itgb4
    Sujet
    Synonyms: Integrin β4 chain
    Pathways
    Integrin Complex
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