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TNFSF9 anticorps

TNFSF9 Reactivité: Humain FACS Hôte: Souris Monoclonal C65 unconjugated
N° du produit ABIN2688965
  • Antigène Voir toutes TNFSF9 Anticorps
    TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
    Reactivité
    • 59
    • 30
    • 15
    Humain
    Hôte
    • 42
    • 20
    • 10
    • 2
    Souris
    Clonalité
    • 37
    • 34
    • 2
    Monoclonal
    Conjugué
    • 41
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TNFSF9 est non-conjugé
    Application
    • 48
    • 37
    • 31
    • 13
    • 13
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Marque
    BD Pharmingen™
    Attributs du produit
    Reacts with a type II membrane protein known as 4-1BB ligand. This molecule belongs to the TNF superfamily. It has been reported to have costimulatory function on activated T cells. Reports suggest that stimulation of activated T cells via 4-1BB ligand does not require the presence of other costimulatory molecules, including CD28. Some studies have reported human 4-1BB ligand to be expressed preferentially on primary B cells and B-cell lines. C65-485 antibody is able to react with recombinant human 4-1BB ligand (rh4-1BBL) bound to CD137 (4-1BB receptor) expressed on PHA-stimulated PBMC. Profile of Hut-78 cell line analzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD137 Ligand - Purified - Clone C65-485 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Clone
    C65
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TNFSF9 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C.
  • Melero, Bach, Hellström, Aruffo, Mittler, Chen: "Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway." dans: European journal of immunology, Vol. 28, Issue 3, pp. 1116-21, (1998) (PubMed).

    Chu, DeBenedette, Stiernholm, Barber, Watts: "Role of IL-12 and 4-1BB ligand in cytokine production by CD28+ and CD28- T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 7, pp. 3081-9, (1997) (PubMed).

    DeBenedette, Shahinian, Mak, Watts: "Costimulation of CD28- T lymphocytes by 4-1BB ligand." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 2, pp. 551-9, (1997) (PubMed).

    Zhou, Kim, Hurtado, Lee, Kim, Pollok, Kwon: "Characterization of human homologue of 4-1BB and its ligand." dans: Immunology letters, Vol. 45, Issue 1-2, pp. 67-73, (1995) (PubMed).

  • Antigène
    TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
    Autre désignation
    CD137 Ligand (TNFSF9 Produits)
    Synonymes
    anticorps TNFSF9, anticorps 4-1BB-L, anticorps 4-1BBL, anticorps AI848817, anticorps Cd137l, anticorps Ly63l, anticorps CD137L, anticorps TNF superfamily member 9, anticorps tumor necrosis factor (ligand) superfamily, member 9, anticorps Tnfsf9, anticorps LOC476729, anticorps TNFSF9
    Sujet
    Synonyms: 4-1BB Ligand
    Pathways
    Activated T Cell Proliferation, Cancer Immune Checkpoints
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