CD151 anticorps

N° du produit ABIN2688986

Détail du produit anti-CD151 anticorps

Antigène: CD151

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD151 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Marque: BD Pharmingen™

Attributs du produit: Reacts with platelet-endothelial cell tetraspan antigen-3 (PETA-3), a 27 kD membrane glycoprotein, expressed on platelets, megakaryocytes, lymphocytes (weak), monocytes, endothelial cells and epithelial cells. PETA-3 (CD151) associates with β1 integrin in certain tissues. This has also been shown with other tetraspan superfamily members, like CD9, CD63 and α5β1. Reports indicate that this association or colocalization of CD151 with β1 integrin in tissues suggests a functional role of this molecule, however, this role has not been elucidated yet. It has also been reported that antibody 14A2.H1 is capable of platelet activation in vitro. Studies showed that different clones of CD151 monoclonal antibodies display strikingly different patterns of binding to human haemopoietic cells and tissue sections, and that this is due at least in part to the presence of the protein in complexes with different integrins. Profile of peripheral blood platelets analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD151 - Purified - Clone 14A2.H1 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: 14A2-H1

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-CD151 (ABIN2688986)

Geary, Cambareri, Sincock, Fitter, Ashman: "Differential tissue expression of epitopes of the tetraspanin CD151 recognised by monoclonal antibodies." dans: Tissue antigens, Vol. 58, Issue 3, pp. 141-53, (2001) (PubMed).

Sincock, Mayrhofer, Ashman: "Localization of the transmembrane 4 superfamily (TM4SF) member PETA-3 (CD151) in normal human tissues: comparison with CD9, CD63, and alpha5beta1 integrin." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 45, Issue 4, pp. 515-25, (1997) (PubMed).

Fitter, Tetaz, Berndt, Ashman: "Molecular cloning of cDNA encoding a novel platelet-endothelial cell tetra-span antigen, PETA-3." dans: Blood, Vol. 86, Issue 4, pp. 1348-55, (1995) (PubMed).

Détails sur CD151

Antigène: CD151

Autre désignation: CD151 (CD151 Produits)

Synonymes: anticorps CD151, anticorps MGC83668, anticorps gp27, anticorps mer2, anticorps raph, anticorps sfa1, anticorps peta-3, anticorps tspan24, anticorps PETA-3, anticorps SFA-1, anticorps Tspan24, anticorps GP27, anticorps MER2, anticorps RAPH, anticorps SFA1, anticorps TSPAN24, anticorps CD151 molecule, anticorps CD151 molecule (Raph blood group) L homeolog, anticorps CD151 molecule (Raph blood group), anticorps CD151 antigen, anticorps CD151, anticorps cd151.L, anticorps cd151, anticorps Cd151

Sujet: Synonyms: PETA-3