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FCER2 anticorps (Biotin)

FCER2 Reactivité: Humain FACS, ELISA Hôte: Souris Monoclonal M Biotin
N° du produit ABIN2689107
  • Antigène Voir toutes FCER2 Anticorps
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Reactivité
    • 104
    • 58
    • 11
    Humain
    Hôte
    • 63
    • 47
    • 24
    Souris
    Clonalité
    • 90
    • 42
    • 2
    Monoclonal
    Conjugué
    • 58
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    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    Cet anticorp FCER2 est conjugé à/à la Biotin
    Application
    • 81
    • 55
    • 36
    • 20
    • 16
    • 13
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
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    Flow Cytometry (FACS), ELISA
    Marque
    BD Pharmingen™
    Attributs du produit
    The M-L233 antibody reacts with the low affinity receptor for human IgE, FcεRII/CD23. CD23 is a type II membrane protein which can be expressed by B cells, monocytes, macrophages, eosinophils, platelets, and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23+ cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 37-25 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types. Profile of peripheral blood lymphocytes analyzed on a FACScan

    BD Pharmingen™ Biotin Mouse Anti-Human CD23 - Biotin - Clone M-L233 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.5 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Clone
    M
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product FCER2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
  • Rieber, Rank, Köhler, Krauss: "Membrane expression of Fc epsilon RII/CD23 and release of soluble CD23 by follicular dendritic cells." dans: Advances in experimental medicine and biology, Vol. 329, pp. 393-8, (1993) (PubMed).

    Conrad: "Fc epsilon RII/CD23: the low affinity receptor for IgE." dans: Annual review of immunology, Vol. 8, pp. 623-45, (1990) (PubMed).

    Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).

  • Antigène
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Autre désignation
    CD23 (FCER2 Produits)
    Synonymes
    anticorps BLAST-2, anticorps CD23, anticorps CD23A, anticorps CLEC4J, anticorps FCE2, anticorps IGEBF, anticorps Fcer2a, anticorps Fc fragment of IgE receptor II, anticorps FCER2, anticorps Fcer2
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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