SOX9 anticorps

N° du produit ABIN272082

Détail du produit anti-SOX9 anticorps

Antigène: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX9 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of SOX-9 protein. (region surrounding Gln175).

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1/5000approx. 1/10000Western Blot: 1/500approx. 1/1000Immunohistochemistry (Paraffin): 1/50approx. 1/200Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-SOX9 (ABIN272082)

Ichikawa, Watahiki, Nampo, Nose, Yamamoto, Irie, Mishima, Maki: "Differences in the developmental origins of the periosteum may influence bone healing." dans: Journal of periodontal research, Vol. 50, Issue 4, pp. 468-78, (2016) (PubMed).

Zhang, Ding, Nie, Li-Ling, Zhang, Zhang, Chen, Li, Ding: "Association of hsa-miR‑145 overexpression in human testicular cells with male infertility." dans: Molecular medicine reports, Vol. 11, Issue 6, pp. 4365-72, (2015) (PubMed).

Nagappan, Park, Park, Kim, Hong, Kang, Zhang, Kim, Lee, Won, Kim: "Proteomic analysis of differentially expressed proteins in vitamin C-treated AGS cells." dans: BMC biochemistry, Vol. 14, pp. 24, (2014) (PubMed).

Détails sur SOX9

Antigène: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Autre désignation: SOX9 (SOX9 Produits)

Synonymes: anticorps CMD1, anticorps CMPD1, anticorps SRA1, anticorps LOC100227849, anticorps 2010306G03Rik, anticorps AV220920, anticorps mKIAA4243, anticorps SOX-9, anticorps cmd1, anticorps cmpd1, anticorps sox-9, anticorps sox9, anticorps sox9-a, anticorps sox9-b, anticorps sox9b, anticorps sra1, anticorps SRY-box 9, anticorps transcription factor SOX-9, anticorps SRY (sex determining region Y)-box 9, anticorps SRY box 9, anticorps SRY-box 9 L homeolog, anticorps SOX9, anticorps LOC100227849, anticorps Sox9, anticorps sox9.L

Sujet: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.Synonyms: CMD1, CMPD1, SRA1, SRY (sex determining region Y)-box 9, SRY-box 9, Transcription factor SOX-9

Poids moléculaire: approx. 56 kDa

ID gène: 6662

NCBI Accession: NP_000337

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development