CDKL2 anticorps
-
- Antigène Voir toutes CDKL2 Anticorps
- CDKL2 (Cyclin Dependent Kinase Like 2 (CDKL2))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CDKL2 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of KKIAMRE protein. (region surrounding Leu240)
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Pureté
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product CDKL2 Anticorps primaire
-
-
- Indications d'application
-
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- DO NOT FREEZE!
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
-
- Antigène
- CDKL2 (Cyclin Dependent Kinase Like 2 (CDKL2))
- Autre désignation
- CDKL2 (CDKL2 Produits)
- Synonymes
- anticorps KKIAMRE, anticorps P56, anticorps CDKL2, anticorps 5330436L21Rik, anticorps AI505225, anticorps Kkm, anticorps DKFZp459L235, anticorps kkiamre, anticorps cyclin dependent kinase like 2, anticorps cyclin-dependent kinase-like 2 (CDC2-related kinase), anticorps cyclin dependent kinase like 2 L homeolog, anticorps CDKL2, anticorps Cdkl2, anticorps cdkl2.L
- Sujet
- The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.Synonyms: Cyclin-dependent kinase-like 2, KKIAMRE, Protein kinase p56 KKIAMRE, Serine/threonine-protein kinase KKIAMRE
- Poids moléculaire
- approx. 56 kDa
- ID gène
- 8999
- NCBI Accession
- NP_003939
- UniProt
- Q92772
-