Liver Arginase anticorps (N-Term)

N° du produit ABIN2773866

Détail du produit anti-Liver Arginase anticorps

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Lapin, Boeuf (Vache), Chien, Porc, Cheval, Chévre, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Liver Arginase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: HSLAIGSISG HARVHPDLGV IWVDAHTDIN TPLTTTSGNL HGQPVSFLLK

Réactivité croisée: Boeuf (Vache), Chien, Humain, Souris, Porc, Lapin, Rat (Rattus)

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ARG1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ARG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 322 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Liver Arginase (ABIN2773866)

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." dans: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Détails sur Liver Arginase

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Autre désignation: Arginase-1 (ARG1 Produits)

Synonymes: anticorps SI:zC146F4.4 (novel protein with NUDIX domain), anticorps si:ch211-146f4.3, anticorps argi1, anticorps AI, anticorps AI256583, anticorps Arg-1, anticorps PGIF, anticorps arginase 1, anticorps arginase, anticorps Arginase-1, anticorps arginase, liver, anticorps L-arginase, anticorps arg1, anticorps PGTG_16455, anticorps argi1, anticorps ARG1, anticorps Arg1

Sujet: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. The type I isoform of ARG1, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.
Protein Interaction Partner: RPA3, RPA2, RPA1, SUZ12, EZH2, BMI1, ALDH4A1, ESR1, RAD21, UBC, UCHL5, ATG101, USP53, FLOT1, NOS1, ARG2,
Protein Size: 322

Poids moléculaire: 35 kDa

ID gène: 383

NCBI Accession: NM_000045, NP_000036

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin